Advancing the global public health agenda for NAFLD: a consensus statement

JV Lazarus, HE Mark, QM Anstee, JP Arab… - Nature Reviews …, 2022 - nature.com
Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease that affects
approximately one-quarter of the global adult population, causing a substantial burden of ill …

Geographical similarity and differences in the burden and genetic predisposition of NAFLD

TCF Yip, E Vilar‐Gomez, S Petta, Y Yilmaz… - Hepatology, 2023 - journals.lww.com
NAFLD has become a major public health problem for more than 2 decades with a growing
prevalence in parallel with the epidemic of obesity and type 2 diabetes (T2D). The disease …

MAFLD enhances clinical practice for liver disease in the Asia-Pacific region

T Kawaguchi, T Tsutsumi, D Nakano… - Clinical and …, 2021 - pmc.ncbi.nlm.nih.gov
Fatty liver is now a major cause of liver disease in the Asia-Pacific region. Liver diseases in
this region have distinctive characteristics. First, fatty liver is frequently observed in …

Lipid accumulation product (LAP) index for the diagnosis of nonalcoholic fatty liver disease (NAFLD): a systematic review and meta-analysis

M Ebrahimi, SA Seyedi, SA Nabipoorashrafi… - Lipids in Health and …, 2023 - Springer
Background Lipid accumulation product (LAP) is an index calculated by waist circumference
(WC) and triglyceride (TG), which reflects lipid toxicity. This study aims to investigate the …

Splicing factor SRSF1 deficiency in the liver triggers NASH-like pathology and cell death

W Arif, B Mathur, MF Saikali, UV Chembazhi… - Nature …, 2023 - nature.com
Regulation of RNA processing contributes profoundly to tissue development and physiology.
Here, we report that serine-arginine-rich splicing factor 1 (SRSF1) is essential for hepatocyte …

[HTML][HTML] Global and national prevalence of nonalcoholic fatty liver disease in adolescents: an analysis of the global burden of disease study 2019

P Hartmann, X Zhang, R Loomba, B Schnabl - Hepatology, 2023 - journals.lww.com
Conclusions: NAFLD in adolescents is an increasing health problem on all continents.
Improving environmental factors, including lifestyle but also healthcare policies, can help to …

[HTML][HTML] From MAFLD to hepatocellular carcinoma and everything in between

SDW Bae, J George, L Qiao - Chinese Medical Journal, 2022 - journals.lww.com
Metabolic (dysfunction) associated fatty liver disease (MAFLD), previously known as non-
alcoholic fatty liver disease, is the most common cause of chronic liver disease worldwide …

The role of iron metabolism in chronic diseases related to obesity

F Qiu, L Wu, G Yang, C Zhang, X Liu, X Sun, X Chen… - Molecular …, 2022 - Springer
Obesity is one of the major public health problems threatening the world, as well as a
potential risk factor for chronic metabolic diseases. There is growing evidence that iron …

The effects of conjugated linoleic acid supplementation on liver function enzymes and malondialdehyde in adults: A GRADE-assessed systematic review and dose …

N Haghighat, G Shimi, F Shiraseb, A Karbasi… - Pharmacological …, 2022 - Elsevier
Background Previous research reported inconsistent findings regarding the effects of
conjugated linoleic acid (CLA) supplementation on liver enzymes. This systematic review …

Chronic jet lag alters gut microbiome and mycobiome and promotes the progression of MAFLD in HFHFD-fed mice

R Zheng, X Xiang, Y Shi, A Qiu, X Luo, J Xie… - Frontiers in …, 2023 - frontiersin.org
Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most common chronic
liver disease worldwide. Circadian disruptors, such as chronic jet lag (CJ), may be new risk …