Introduction: Drug discovery is the process through which potential new compounds are
identified by means of biology, chemistry, and pharmacology. Due to the high complexity of …

The complexity of orphan diseases, which are those that do not have an effective treatment,
together with the high dimensionality of the genetic data used for their analysis and the high …

Aims It is known that matrix metalloproteinase (MMP)‐11 has a role in tumour development
and progression, and also that immune cells can influence cancer cells to increase their …

The emerging UAV network suffers from severe security risks from attackers. If the attackers
sneak into an Internet of UAV (IoU) network, they would occupy the scarce resources which …

In this paper, we introduce the holdout sampler to find the defective pathways in high
underdetermined phenotype prediction problems. This sampling algorithm is inspired by the …

Background To understand the transcriptomic response to SARS-CoV-2 infection, is of the
utmost importance to design diagnostic tools predicting the severity of the infection. Methods …

We present the analysis of the defective genetic pathways of the Late-Onset Alzheimer's
Disease (LOAD) compared to the Mild Cognitive Impairment (MCI) and Healthy Controls …

Sarcopenia is an age-related multifactorial process that involved several biological
mechanisms, whose specific contribution and interplay is still unknown. The present study …

Background Phenotype prediction problems are usually considered ill-posed, as the amount
of samples is very limited with respect to the scrutinized genetic probes. This fact …

We present the analysis of defective pathways in multiple myeloma (MM) using two recently
developed sampling algorithms of the biological pathways: The Fisher's ratio sampler, and …