Dietary phytochemicals in colorectal cancer prevention and treatment: A focus on the molecular mechanisms involved
Worldwide, colorectal cancer (CRC) remains a major cancer type and leading cause of
death. Unfortunately, current medical treatments are not sufficient due to lack of effective …
death. Unfortunately, current medical treatments are not sufficient due to lack of effective …
Resveratrol as sensitizer in colorectal cancer plasticity
Despite tremendous medical treatment successes, colorectal cancer (CRC) remains a
leading cause of cancer deaths worldwide. Chemotherapy as monotherapy can lead to …
leading cause of cancer deaths worldwide. Chemotherapy as monotherapy can lead to …
Naturally occurring immunomodulators with antitumor activity: An insight on their mechanisms of action
Natural products with immunomodulatory activity are widely used in treatment of many
diseases including autoimmune diseases, inflammatory disorders in addition to cancer …
diseases including autoimmune diseases, inflammatory disorders in addition to cancer …
Quercetin Alleviates Intestinal Oxidative Damage Induced by H2O2 via Modulation of GSH: In Vitro Screening and In Vivo Evaluation in a Colitis Model of Mice
The gastrointestinal tract is exposed to pro-oxidants from food, host immune factors, and
microbial pathogens, which may induce oxidative damage. Oxidative stress has been shown …
microbial pathogens, which may induce oxidative damage. Oxidative stress has been shown …
Zein nanoparticles as low-cost, safe, and effective carriers to improve the oral bioavailability of resveratrol
R Nunes, A Baião, D Monteiro, J das Neves… - Drug Delivery and …, 2020 - Springer
The clinical translation of the multiple pharmacological effects of resveratrol (RSV) found in
preclinical studies has been impaired by its poor bioavailability, due to poor solubility and …
preclinical studies has been impaired by its poor bioavailability, due to poor solubility and …
[HTML][HTML] Applications of resveratrol in the treatment of gastrointestinal cancer
Natural product compounds have lately attracted interest in the scientific community as a
possible treatment for gastrointestinal (GI) cancer, due to their anti-inflammatory and …
possible treatment for gastrointestinal (GI) cancer, due to their anti-inflammatory and …
[HTML][HTML] A multi-targeted approach to suppress tumor-promoting inflammation
Cancers harbor significant genetic heterogeneity and patterns of relapse following many
therapies are due to evolved resistance to treatment. While efforts have been made to …
therapies are due to evolved resistance to treatment. While efforts have been made to …
Intensification of resveratrol cytotoxicity, pro-apoptosis, oxidant potentials in human colorectal carcinoma HCT-116 cells using zein nanoparticles
MT Khayat, MA Zarka, DFA El-Telbany… - Scientific Reports, 2022 - nature.com
Abstract Resveratrol (RSV), a non-flavonoid stilbene polyphenol, possesses anti-
carcinogenic activities against all the major stages of cancer. Zein nanoparticles (ZN NPs) …
carcinogenic activities against all the major stages of cancer. Zein nanoparticles (ZN NPs) …
Resveratrol inhibits cancer cell proliferation by impairing oxidative phosphorylation and inducing oxidative stress
S Rodríguez-Enríquez, SC Pacheco-Velázquez… - Toxicology and applied …, 2019 - Elsevier
The resveratrol (RSV) efficacy to affect the proliferation of several cancer cell lines was
initially examined. RSV showed higher potency to decrease growth of metastatic HeLa and …
initially examined. RSV showed higher potency to decrease growth of metastatic HeLa and …
Properties and molecular mechanisms of resveratrol: a review
T Yang, L Wang, M Zhu, L Zhang… - Die Pharmazie-An …, 2015 - ingentaconnect.com
Resveratrol, for example widely present in the Chinese herbal medicine Polygonum
cuspidatum, it is a natural phytoalexin, and has many biochemical activities, such as anti …
cuspidatum, it is a natural phytoalexin, and has many biochemical activities, such as anti …