Obesity is a global epidemic representing a serious public health burden as it is a major risk
factor for the development of cardiovascular disease, stroke and all-cause mortality. Chronic …

Macrophages, the central mediators of innate immune responses, being in the first-line of
defense, they have to readily respond to pathogenic or tissue damage signals to initiate the …

Trained innate immunity, induced via modulation of mature myeloid cells or their bone
marrow progenitors, mediates sustained increased responsiveness to secondary …

We determined whether gut microbiota-produced trimethylamine (TMA) is oxidized into
trimethylamine N-oxide (TMAO) in nonliver tissues and whether TMAO promotes …

Low-grade systemic inflammation is a key pathophysiological component of atherosclerotic
cardiovascular disease (CVD), and long-term activation of myeloid cells is thought to be …

The comprehensive anabolic effects of insulin throughout the body, in addition to the control
of glycemia, include ensuring lipid homeostasis and anti-inflammatory modulation …

To characterize transcriptomic changes in endothelial cells (ECs) infected by coronaviruses,
and stimulated by DAMPs, the expressions of 1311 innate immune regulatomic genes (IGs) …

Obesity, a metabolic disorder characterized by excessive accumulation of adipose tissue,
has globally become an increasingly prevalent disease. Extensive studies have been …

Aim Studies on the effect of Ramadan diurnal intermittent fasting (RDIF) on glucometabolic
markers have yielded conflicting results. We conducted a meta-analysis to estimate the …

Non‐alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic
syndrome, being a common comorbidity of type 2 diabetes and with important links to …