Neuroinflammatory mechanisms in ischemic stroke: focus on cardioembolic stroke, background, and therapeutic approaches

CD Maida, RL Norrito, M Daidone… - International journal of …, 2020 - mdpi.com
One of the most important causes of neurological morbidity and mortality in the world is
ischemic stroke. It can be a result of multiple events such as embolism with a cardiac origin …

A review of neutrophil extracellular traps (NETs) in disease: potential anti-NETs therapeutics

V Mutua, LJ Gershwin - Clinical reviews in allergy & immunology, 2021 - Springer
Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …

The role of selected pro-inflammatory cytokines in pathogenesis of ischemic stroke

H Pawluk, A Woźniak, G Grześk… - … interventions in aging, 2020 - Taylor & Francis
Stroke is currently one of the most common causes of death and disability in the world, and
its pathophysiology is a complex process, involving the oxidative stress and inflammatory …

Neutrophil extracellular traps are increased in patients with acute ischemic stroke: prognostic significance

J Vallés, A Lago, MT Santos, AM Latorre… - Thrombosis and …, 2017 - thieme-connect.com
Neutrophil extracellular traps (NETs) are networks of DNA, histones, and proteolytic
enzymes produced by activated neutrophils through different mechanisms. NET formation is …

Inflammatory cytokines in acute ischemic stroke

A Tuttolomondo, D Di Raimondo… - Current …, 2008 - ingentaconnect.com
Three major cytokines, namely, tumor necrosis factor (TNF-α), interleukin (IL)-1, and IL-6 are
produced by cultured brain cells after various stimuli such as ischemia. Neurones …

Blood markers of coagulation, fibrinolysis, endothelial dysfunction and inflammation in lacunar stroke versus non-lacunar stroke and non-stroke: systematic review and …

S Wiseman, F Marlborough, F Doubal… - Cerebrovascular …, 2014 - karger.com
Background: The cause of cerebral small vessel disease is not fully understood, yet it is
important, accounting for about 25% of all strokes. It also increases the risk of having …

Mechanisms of poststroke fatigue

W De Doncker, R Dantzer, H Ormstad… - Journal of Neurology …, 2018 - jnnp.bmj.com
Mechanisms of poststroke fatigue | Journal of Neurology, Neurosurgery & Psychiatry Skip to
main content Viewing from: Google Indexer BMJ Journals Subscribe Log In More Log in via …

Inflammatory molecules might become both biomarkers and therapeutic targets for stroke management

L Ramiro, A Simats… - Therapeutic …, 2018 - journals.sagepub.com
Stroke is the fifth leading cause of death and the most frequent cause of disability worldwide.
Currently, stroke diagnosis is based on neuroimaging; therefore, the lack of a rapid tool to …

Inflammation in ischemic stroke subtypes

A Tuttolomondo, D Di Raimondo… - Current …, 2012 - ingentaconnect.com
Determining the cause of stroke does influence choices for management. categorization of
subtypes of ischemic stroke has had considerable study, but definitions are hard to formulate …

Serum levels of cytokines and C-reactive protein in acute ischemic stroke patients, and their relationship to stroke lateralization, type, and infarct volume

H Ormstad, HCD Aass, N Lund-Sørensen… - Journal of …, 2011 - Springer
There is increasing evidence that inflammation plays an important role in the progression of
acute ischemic stroke (AIS). The primary aims of this study were to examine the serum levels …