The etiology of hepatocellular carcinoma and consequences for treatment

AJ Sanyal, SK Yoon, R Lencioni - The oncologist, 2010 - academic.oup.com
Most patients with hepatocellular carcinoma (HCC) have liver cirrhosis, which develops
following long periods of chronic liver disease. Cirrhosis is characterized by a decrease in …

Alcohol and cancer: Mechanisms and therapies

A Ratna, P Mandrekar - Biomolecules, 2017 - mdpi.com
Several scientific and clinical studies have shown an association between chronic alcohol
consumption and the occurrence of cancer in humans. The mechanism for alcohol-induced …

[PDF][PDF] General oncology care in Egypt

AH Ibrahim, E Shash - Cancer in the Arab world, 2022 - library.oapen.org
The Egyptian population is one of the largest in the Middle East and North Africa region.
Egypt is home to a population of 99,842,504, according to the latest official census in …

[HTML][HTML] Management of hepatitis C virus genotype 4: recommendations of an international expert panel

MA Khattab, P Ferenci, SJ Hadziyannis, M Colombo… - Journal of …, 2011 - Elsevier
HCV has been classified into no fewer than six major genotypes and a series of subtypes.
Each HCV genotype is unique with respect to its nucleotide sequence, geographic …

The molecular epidemiology of chronic aflatoxin driven impaired child growth

PC Turner - Scientifica, 2013 - Wiley Online Library
Aflatoxins are toxic secondary fungal metabolites that contaminate dietary staples in tropical
regions; chronic high levels of exposure are common for many of the poorest populations …

Aflatoxin B1-induced reproductive toxicity in male rats: possible mechanism of action

C Supriya, BP Girish, PS Reddy - International journal of …, 2014 - journals.sagepub.com
Aflatoxin B1 (AFB1), one of the most common mycotoxins found in human foods, is
principally hepatotoxic; however, it also affects reproduction. The aim of the present study …

Rethinking breast cancer screening strategies in resource-limited settings

M Galukande, E Kiguli-Malwadde - African health sciences, 2010 - ajol.info
The incidence of breast cancer in sub-Saharan nations is increasing. There is a worsening
scarcity of Human Resource for Health in Uganda in particular and Sub Saharan Africa in …

Circulating IL-6, IL-17 and vitamin D in hepatocellular carcinoma: potential biomarkers for a more favorable prognosis?

LN Hammad, SM Abdelraouf… - Journal of …, 2013 - Taylor & Francis
Hepatitis C virus (HCV) infects primarily hepatocytes, leads to development of fibrosis and/or
cirrhosis of the liver and is a significant factor for developing hepatocellular carcinoma …

Relevance of serum levels of interleukin-6 and syndecan-1 in patients with hepatocellular carcinoma

HA Metwaly, MMH Al-Gayyar, S Eletreby… - Scientia …, 2011 - pmc.ncbi.nlm.nih.gov
Syndecan-1 is a trans-membrane heparan sulfate proteoglycan that localizes in epithelial
cells and has been shown to be present in normal hepatocytes. It is thought to be involved in …

Serum Levels of Interleukin‐6 and Interleukin‐10 as Biomarkers for Hepatocellular Carcinoma in Egyptian Patients

MS Othman, AM Aref, AA Mohamed… - International Scholarly …, 2013 - Wiley Online Library
Interleukin‐10 (IL‐10) and interleukin‐6 (IL‐6) have been reported to be related to
hepatocellular carcinoma (HCC) prognosis. This study aimed to investigate the clinical …