Association between lead exposure and DNA damage (genotoxicity): systematic review and meta-analysis

R Nagaraju, R Kalahasthi, R Balachandar… - Archives of …, 2022 - Springer
Studies suggest that chronic lead (Pb) exposure may induce deoxyribonucleic acid (DNA)
damage. However, there is no synthesised evidence in this regard. We systematically …

The Comet Assay as a Tool in Human Biomonitoring Studies of Environmental and Occupational Exposure to Chemicals—A Systematic Scoping Review

C Ladeira, P Møller, L Giovannelli, G Gajski, A Haveric… - Toxics, 2024 - mdpi.com
Biomonitoring of human populations exposed to chemical substances that can act as
potential mutagens or carcinogens, may enable the detection of damage and early disease …

Ameliorative effects of Moringa oleifera seeds and leaves on chlorpyrifos-induced growth retardation, immune suppression, oxidative stress, and DNA damage in …

RE Ibrahim, W El-Houseiny, A Behairy, MF Mansour… - Aquaculture, 2019 - Elsevier
Chlorpyrifos (CPF) is one of the most highly prevalent insecticides in freshwater ecosystems
and has been widely detected in fishery and agricultural products worldwide. Moringa …

Oxidative DNA damage and oxidative stress in lead-exposed workers

M Dobrakowski, N Pawlas… - Human & …, 2017 - journals.sagepub.com
There are many discrepancies among the results of studies on the genotoxicity of lead. The
aim of the study was to explore lead-induced DNA damage, including oxidative damage, in …

Blood lead and cadmium levels in occupationally exposed workers and their effect on markers of DNA damage and repair

P Singh, P Mitra, T Goyal, S Sharma… - … Geochemistry and Health, 2021 - Springer
Occupational exposure to heavy metals like lead and cadmium causes a wide range of
biological effects and may elevate the risk of genetic damage. Heavy metal toxicity is now …

Associations of blood lead levels with multiple genotoxic biomarkers among workers in China: A population-based study

T Wang, Y Tu, K Wang, S Gong, G Zhang, Y Zhang… - Environmental …, 2021 - Elsevier
Carcinogenic effects from low doses of lead (Pb) exposure to populations have been
suspected but not concluded. Therefore, a large-scale cross-sectional study was conducted …

Lead induces DNA damage and alteration of ALAD and antioxidant genes mRNA expression in construction site workers

Z Akram, S Riaz, MA Kayani, S Jahan… - … of environmental & …, 2019 - Taylor & Francis
Oxidative stress and DNA damage are considered as possible mechanisms involved in lead
toxicity. To test this hypothesis, DNA damage and expression variations of aminolevulinic …

Chronic Exposure to Lead Causes Neurotoxicity by Generating Oxidative Stress and Inducing DNA Damages in Zebrafish Brain: Involvement of Nrf2-Keap1 …

KK Dey, S Kamila, T Das, A Chattopadhyay - Biological Trace Element …, 2025 - Springer
Toxicity of lead (Pb) causes several health problems in human beings. The present study
reveals the potential effects of Pb on adult zebrafish (Danio rerio) brain at an …

Structural and lipid peroxidation effects of lead on rat hippocampus and its attenuation by hydrogen rich water

MG Paulis, OA Hassan, MF Abbass… - Journal of Chemical …, 2018 - Elsevier
Despite the well-known toxicity and the efforts to control its exposure, lead still has a serious
health concern, particularly in young ages. Chelation therapy cannot correct the …

Blood lead levels among the occupationally exposed workers and its effect on calcium and vitamin D metabolism: A case-control study

J Batra, A Thakur, SK Meena, L Singh… - Journal of family …, 2020 - journals.lww.com
Materials and Methods: This cross-sectional, case-control study was conducted for a period
of 18 months (January 2017 to July 2018). A total of 160 subjects were included in the study …