Common mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disorders

R Gao, P Penzes - Current molecular medicine, 2015 - ingentaconnect.com
Autism Spectrum Disorders (ASD) and Schizophrenia (SCZ) are cognitive disorders with
complex genetic architectures but overlapping behavioral phenotypes, which suggests …

Altered neuronal and circuit excitability in fragile X syndrome

A Contractor, VA Klyachko, C Portera-Cailliau - Neuron, 2015 - cell.com
Fragile X syndrome (FXS) results from a genetic mutation in a single gene yet produces a
phenotypically complex disorder with a range of neurological and psychiatric problems …

The attentive brain: insights from developmental cognitive neuroscience

D Amso, G Scerif - Nature Reviews Neuroscience, 2015 - nature.com
Visual attention functions as a filter to select environmental information for learning and
memory, making it the first step in the eventual cascade of thought and action systems. Here …

GABAergic interneurons shape the functional maturation of the cortex

C Le Magueresse, H Monyer - Neuron, 2013 - cell.com
From early embryonic development to adulthood, GABA release participates in the
construction of the mammalian cerebral cortex. The maturation of GABAergic …

[HTML][HTML] Inhibitory control of the excitatory/inhibitory balance in psychiatric disorders

M Selten, H van Bokhoven, NN Kasri - F1000Research, 2018 - ncbi.nlm.nih.gov
Neuronal networks consist of different types of neurons that all play their own role in order to
maintain proper network function. The two main types of neurons segregate in excitatory and …

Lessons learned from studying syndromic autism spectrum disorders

Y Sztainberg, HY Zoghbi - Nature neuroscience, 2016 - nature.com
Syndromic autism spectrum disorders represent a group of childhood neurological
conditions, typically associated with chromosomal abnormalities or mutations in a single …

GABA system dysfunction in autism and related disorders: from synapse to symptoms

S Coghlan, J Horder, B Inkster, MA Mendez… - Neuroscience & …, 2012 - Elsevier
Autism spectrum disorders (ASDs) are neurodevelopmental syndromes characterised by
repetitive behaviours and restricted interests, impairments in social behaviour and relations …

Molecular mechanisms of fragile X syndrome: a twenty-year perspective

MR Santoro, SM Bray, ST Warren - Annual Review of Pathology …, 2012 - annualreviews.org
Fragile X syndrome (FXS) is a common form of inherited intellectual disability and is one of
the leading known causes of autism. The mutation responsible for FXS is a large expansion …

GABAergic system dysfunction in autism spectrum disorders

H Zhao, X Mao, C Zhu, X Zou, F Peng… - Frontiers in cell and …, 2022 - frontiersin.org
Autism spectrum disorder (ASD) refers to a series of neurodevelopmental diseases
characterized by two hallmark symptoms, social communication deficits and repetitive …

Fragile X syndrome

RJ Hagerman, E Berry-Kravis, HC Hazlett… - Nature reviews Disease …, 2017 - nature.com
Fragile X syndrome (FXS) is the leading inherited form of intellectual disability and autism
spectrum disorder, and patients can present with severe behavioural alterations, including …