The Yin and Yang of TLR4 in COVID-19
S Mukherjee, J Bayry - Cytokine & Growth Factor Reviews, 2024 - Elsevier
Various pattern recognition receptors (PRRs), including toll-like receptors (TLRs), play a
crucial role in recognizing invading pathogens as well as damage-associated molecular …
crucial role in recognizing invading pathogens as well as damage-associated molecular …
Revisiting the dimensions of universal vaccine with special focus on COVID-19: Efficacy versus methods of designing
P Jaishwal, K Jha, SP Singh - International Journal of Biological …, 2024 - Elsevier
Even though the use of SARS-CoV-2 vaccines during the COVID-19 pandemic showed
unprecedented success in a short time, it also exposed a flaw in the current vaccine design …
unprecedented success in a short time, it also exposed a flaw in the current vaccine design …
[HTML][HTML] Cell Surface Fibroblast Activation Protein-2 (Fap2) of Fusobacterium nucleatum as a Vaccine Candidate for Therapeutic Intervention of Human Colorectal …
Colorectal cancer (CRC) is one of the most common cancers and is the second-highest in
cancer-related deaths worldwide. The changes in gut homeostasis and microbial dysbiosis …
cancer-related deaths worldwide. The changes in gut homeostasis and microbial dysbiosis …
Comparative Binding Ability of Human Monoclonal Antibodies against Omicron Variants of SARS-CoV-2: An In Silico Investigation
Mutation (s) in the spike protein is the major characteristic trait of newly emerged SARS-CoV-
2 variants such as Alpha (B. 1.1. 7), Beta (B. 1.351), Gamma (P. 1), Delta (B. 1.617. 2), and …
2 variants such as Alpha (B. 1.1. 7), Beta (B. 1.351), Gamma (P. 1), Delta (B. 1.617. 2), and …
Execution and design of an anti HPIV-1 vaccine with multiple epitopes triggering innate and adaptive immune responses: an immunoinformatic approach
Human Parainfluenza Virus (HPIV) Type-1, which is an anti-sense ribonucleic acid (RNA)
virus belonging to the paramyxoviridae family, induces upper and lower respiratory tract …
virus belonging to the paramyxoviridae family, induces upper and lower respiratory tract …
SARS-CoV-2 activates the TLR4/MyD88 pathway in human macrophages: A possible correlation with strong pro-inflammatory responses in severe COVID-19
S Sahanic, R Hilbe, C Dünser, P Tymoszuk… - Heliyon, 2023 - cell.com
Abstract Background Toll-like receptors (TLRs) play a pivotal role in the immunologic
response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …
response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection …
In silico identification of potential miRNAs-mRNA inflammatory networks implicated in the pathogenesis of COVID-19
SH Sheikhshabani, Z Amini-Farsani, P Modarres… - Human Gene, 2023 - Elsevier
COVID-19 has been found to affect the expression profile of several mRNAs and miRNAs,
leading to dysregulation of a number of signaling pathways, particularly those related to …
leading to dysregulation of a number of signaling pathways, particularly those related to …
Assessing the efficacy of cinnamon compounds against H. pylori through molecular docking, MD Simulations and ADMET analyses
Antibiotics are the drugs that are used for the management of microbial diseases. However,
these conventional synthetic drugs can harmfully affect the human health. Since …
these conventional synthetic drugs can harmfully affect the human health. Since …
Peptide candidates for the development of therapeutics and vaccines against β-coronavirus infection
Betacoronaviruses (β-CoVs) have caused major viral outbreaks in the last two decades in
the world. The mutation and recombination abilities in β-CoVs resulted in zoonotic diseases …
the world. The mutation and recombination abilities in β-CoVs resulted in zoonotic diseases …
An in silico approach to study the role of epitope order in the multi-epitope-based peptide (MEBP) vaccine design
MR Salaikumaran, PS Kasamuthu… - Scientific Reports, 2022 - nature.com
With different countries facing multiple waves, with some SARS-CoV-2 variants more deadly
and virulent, the COVID-19 pandemic is becoming more dangerous by the day and the …
and virulent, the COVID-19 pandemic is becoming more dangerous by the day and the …