2023 ESC Guidelines for the management of cardiomyopathies: Developed by the task force on the management of cardiomyopathies of the European Society of …

E Arbelo, A Protonotarios, JR Gimeno… - European heart …, 2023 - academic.oup.com
• The specific situation of the patient. Unless otherwise provided for by national regulations,
off-label use of medication should be limited to situations where it is in the patient's interest …

Targeted therapies in pediatric and adult patients with hypertrophic heart disease: from molecular pathophysiology to personalized medicine

E Monda, A Bakalakos, M Rubino, F Verrillo… - Circulation: Heart …, 2023 - Am Heart Assoc
Hypertrophic cardiomyopathy is a myocardial disease defined by an increased left
ventricular wall thickness not solely explained by abnormal loading conditions. It is often …

Inherited arrhythmias in the pediatric population: an updated overview

MV Mariani, N Pierucci, F Fanisio, D Laviola, G Silvetti… - Medicina, 2024 - mdpi.com
Pediatric cardiomyopathies (CMs) and electrical diseases constitute a heterogeneous
spectrum of disorders distinguished by structural and electrical abnormalities in the heart …

Myocardial Scarring and Sudden Cardiac Death in Young Patients With Hypertrophic Cardiomyopathy: A Multicenter Cohort Study

RH Chan, L Van Der Wal, G Liberato, E Rowin… - JAMA …, 2024 - jamanetwork.com
Importance The ability to predict sudden cardiac death (SCD) in children and adolescents
with hypertrophic cardiomyopathy (HCM) is currently inadequate. Late gadolinium …

[HTML][HTML] Syncope in hypertrophic cardiomyopathy (part II): An expert consensus statement on the diagnosis and management

M Brignole, F Cecchi, A Anastasakis, L Crotti… - International journal of …, 2023 - Elsevier
Syncopal events in patients with hypertrophic cardiomyopathy (HCM) are of concern as they
are a vital consideration in algorithms for risk stratification for sudden cardiac death (SCD) …

Indications and management of implantable cardioverter-defibrillator therapy in childhood hypertrophic cardiomyopathy: A position statement from the AEPC Working …

JP Kaski, JAE Kammeraad, NA Blom… - Cardiology in the …, 2023 - cambridge.org
Sudden cardiac death is the most common mode of death during childhood and
adolescence in hypertrophic cardiomyopathy, and identifying those individuals at highest …

Distinguishing left ventricular hypertrophy from hypertrophic cardiomyopathy in adolescents: a longitudinal observation study

MI Forså, MK Smedsrud, KH Haugaa… - European Journal of …, 2024 - academic.oup.com
Aims Echocardiographic characteristics to distinguish physiological left ventricular (LV)
hypertrophy from pathology are warranted in early adolescent athletes. This study aimed to …

[HTML][HTML] Reversed septal curvature is associated with nonsustained ventricular tachycardia in hypertrophic cardiomyopathy

Y He, J Zhou - The American Journal of Cardiology, 2024 - Elsevier
Sudden cardiac death (SCD) is associated with nonsustained ventricular tachycardia
(NSVT) in patients with hypertrophic cardiomyopathy (HCM). Recently, differences regarding …

Clinical and Genetic Screening for Hypertrophic Cardiomyopathy in Paediatric Relatives: Changing Paradigms in Clinical Practice

CM Lawley, JP Kaski - Journal of Clinical Medicine, 2023 - mdpi.com
Hypertrophic cardiomyopathy (HCM) is an important cause of morbidity and mortality in
children. While the aetiology is heterogeneous, most cases are caused by variants in the …

Novel Multiplexed Plasma Biomarker Panel Has Diagnostic and Prognostic Potential in Children With Hypertrophic Cardiomyopathy

G Captur, I Doykov, SC Chung, E Field… - Circulation: Genomic …, 2024 - Am Heart Assoc
BACKGROUND: Hypertrophic cardiomyopathy (HCM) is defined clinically by pathological
left ventricular hypertrophy. We have previously developed a plasma proteomics biomarker …