Regeneration is one of the great mysteries of biology. Planarians are flatworms capable of
dramatic feats of regeneration, which have been studied for over 2 centuries. Recent …

Planarians are a group of flatworms. Some planarian species have remarkable regenerative
abilities, which involve abundant pluripotent adult stem cells. This makes these worms a …

The Ensembl gene annotation system has been used to annotate over 70 different
vertebrate species across a wide range of genome projects. Furthermore, it generates the …

INTRODUCTION The complete sequence of animal genomes has had a transformative
impact on biological research. Whereas the genome sequence of an organism contains the …

Organs that pump luminal fluids by the coordinated beat of motile cilia are integral to animal
physiology. Such organs include the human airways, brain ventricles and reproductive …

Many animal cells assemble single cilia involved in motile and/or sensory functions. In
contrast, multiciliated cells (MCCs) assemble up to 300 motile cilia that beat in a coordinate …

Neoblasts are an abundant, heterogeneous population of adult stem cells (ASCs) that
facilitate the maintenance of planarian tissues and organs, providing a powerful system to …

Planarians have a long history in the fields of developmental and regenerative biology.
These animals have also sparked interest in neuroscience due to their neuroanatomy …

Excretion is an essential physiological process, carried out by all living organisms,
regardless of their size or complexity. 1–3 Both protostomes (eg, flies and flatworms) and …

Planarians regenerate all body parts after injury, including the central nervous system
(CNS). We capitalized on this distinctive trait and completed a gene expression-guided …