Phasic/tonic glial GABA differentially transduce for olfactory adaptation and neuronal aging

H Cheng, D Chen, X Li, U Al-Sheikh, D Duan, Y Fan… - Neuron, 2024 - cell.com
Phasic (fast) and tonic (sustained) inhibition of γ-aminobutyric acid (GABA) are fundamental
for regulating day-to-day activities, neuronal excitability, and plasticity. However, the …

The voltage-gated calcium channel EGL-19 acts on glia to drive olfactory adaptation

D Chen, H Cheng, S Liu, U Al-Sheikh, Y Fan… - Frontiers in Molecular …, 2022 - frontiersin.org
Calcium channelopathies have been strongly linked to cardiovascular, muscular,
neurological and psychiatric disorders. The voltage-gated calcium channels (VGCC) are …

Nematode homologs of the sour taste receptor Otopetrin1 are evolutionarily conserved acid-sensitive proton channels

S Li, U Al-Sheikh, Y Chen, L Kang - Frontiers in Cell and …, 2023 - frontiersin.org
Numerous taste receptors and related molecules have been identified in vertebrates and
invertebrates. Otopetrin1 has recently been identified as mammalian sour taste receptor …