DNA is the central storage molecule of genetic information in the cell, and reading that information is a central problem in biology. While sequencing technology has made …
I Usov, R Mezzenga - Macromolecules, 2015 - ACS Publications
Biological semiflexible polymers and filaments such as collagen, fibronectin, actin, microtubules, coiled-coil proteins, DNA, siRNA, amyloid fibrils, etc., are ubiquitous in nature …
Run-and-tumble motility is widely used by swimming microorganisms including numerous prokaryotic and eukaryotic organisms. Here, we experimentally investigate the run-and …
L Albertazzi, D Van Der Zwaag, CMA Leenders… - Science, 2014 - science.org
Supramolecular fibers are prominent structures in biology and chemistry. A quantitative understanding of molecular exchange pathways in these one-dimensional aggregates was …
An early step in intracellular transport is the selective recognition of a vesicle by its appropriate target membrane, a process regulated by Rab GTPases via the recruitment of …
In this review, we provide an organized summary of the theoretical and computational results that are available for polymers subject to spatial or topological constraints. Because …
J Adamcik, C Lara, I Usov, JS Jeong, FS Ruggeri… - Nanoscale, 2012 - pubs.rsc.org
We report the investigation of the mechanical properties of different types of amyloid fibrils by the peak force quantitative nanomechanical (PF-QNM) technique. We demonstrate that …
The distances over which biological molecules and their complexes can function range from a few nanometres, in the case of folded structures, to millimetres, for example, during …
During aging, changes occur in the collagen network that contribute to various pathological phenotypes in the skeletal, vascular, and pulmonary systems. The aim of this study was to …