Kratom—pharmacology, clinical implications, and outlook: a comprehensive review
SC Eastlack, EM Cornett, AD Kaye - Pain and therapy, 2020 - Springer
Kratom, or Mitragyna, is a tropical plant indigenous to Southeast Asia, with unique
pharmacological properties. It is commonly consumed by preparing the leaves into …
pharmacological properties. It is commonly consumed by preparing the leaves into …
Kratom as an opioid alternative: harm, or harm reduction? A systematic review of literature
ABSTRACT Background: Kratom (Mitragyna speciosa Korth.) products are increasingly
endorsed for self-management of multiple ailments, including as opioid substitution. The …
endorsed for self-management of multiple ailments, including as opioid substitution. The …
Investigation of the adrenergic and opioid binding affinities, metabolic stability, plasma protein binding properties, and functional effects of selected indole-based …
Selected indole-based kratom alkaloids were evaluated for their opioid and adrenergic
receptor binding and functional effects, in vivo antinociceptive effects, plasma protein …
receptor binding and functional effects, in vivo antinociceptive effects, plasma protein …
Past-year kratom use in the US: estimates from a nationally representative sample
JJ Palamar - American journal of preventive medicine, 2021 - Elsevier
Introduction Kratom is a plant with partial opioid agonist effects, and its use has become
popular to ameliorate symptoms of opioid withdrawal. However, use has been linked to …
popular to ameliorate symptoms of opioid withdrawal. However, use has been linked to …
Patterns and reasons for kratom (Mitragyna speciosa) use among current and former opioid poly-drug users
Abstract Ethnopharmacological relevance Kratom (Mitragyna speciosa) is a native medicinal
plant of Southeast Asia widely reported to be used to reduce opioid dependence and …
plant of Southeast Asia widely reported to be used to reduce opioid dependence and …
Exploring the self-reported motivations of kratom (Mitragyna speciosa Korth.) use: a cross-sectional investigation
O Grundmann, CA Veltri, D Morcos… - The American Journal …, 2022 - Taylor & Francis
ABSTRACT Background: Kratom (Mitragyna speciosa Korth.) use outside of Southeast Asia
has increased over the past decade. Objectives: This investigation clarifies kratom's role in …
has increased over the past decade. Objectives: This investigation clarifies kratom's role in …
In vitro and in vivo pharmacology of kratom
Kratom products have been historically and anecdotally used in south Asian countries for
centuries to manage pain and opioid withdrawal. The use of kratom products has …
centuries to manage pain and opioid withdrawal. The use of kratom products has …
Evaluation of kratom opioid derivatives as potential treatment option for alcohol use disorder
AM Gutridge, S Chakraborty, BR Varga… - Frontiers in …, 2021 - frontiersin.org
Background and Purpose: Mitragyna speciosa extract and kratom alkaloids decrease
alcohol consumption in mice at least in part through actions at the δ-opioid receptor (δOR) …
alcohol consumption in mice at least in part through actions at the δ-opioid receptor (δOR) …
Forensic implications of kratom: kratom toxicity, correlation with mitragynine concentrations, and polypharmacy
Abstract Purpose of Review Kratom, a preparation of the leaves collected from the Southeast
Asian plant Mitragyna speciosa, has increased in use within the United States (US) …
Asian plant Mitragyna speciosa, has increased in use within the United States (US) …
Kratom use within the context of the evolving opioid crisis and the COVID-19 pandemic in the United States
WC Prozialeck, PC Lamar, M Krupp, M Moon… - Frontiers in …, 2021 - frontiersin.org
Kratom (Mitragyna speciosa, Korth.) is an evergreen tree that is indigenous to Southeast
Asia. When ingested, kratom leaves or decoctions from the leaves have been reported to …
Asia. When ingested, kratom leaves or decoctions from the leaves have been reported to …