Protein analysis by shotgun/bottom-up proteomics
According to Genome Sequencing Project statistics (http://www. ncbi. nlm. nih.
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …
gov/genomes/static/gpstat. html), as of February 16, 2012, complete gene sequences have …
A survey of computational methods and error rate estimation procedures for peptide and protein identification in shotgun proteomics
AI Nesvizhskii - Journal of proteomics, 2010 - Elsevier
This manuscript provides a comprehensive review of the peptide and protein identification
process using tandem mass spectrometry (MS/MS) data generated in shotgun proteomic …
process using tandem mass spectrometry (MS/MS) data generated in shotgun proteomic …
MSBooster: improving peptide identification rates using deep learning-based features
Peptide identification in liquid chromatography-tandem mass spectrometry (LC-MS/MS)
experiments relies on computational algorithms for matching acquired MS/MS spectra …
experiments relies on computational algorithms for matching acquired MS/MS spectra …
The quantitative proteome of a human cell line
The generation of mathematical models of biological processes, the simulation of these
processes under different conditions, and the comparison and integration of multiple data …
processes under different conditions, and the comparison and integration of multiple data …
iProphet: multi-level integrative analysis of shotgun proteomic data improves peptide and protein identification rates and error estimates
The combination of tandem mass spectrometry and sequence database searching is the
method of choice for the identification of peptides and the mapping of proteomes. Over the …
method of choice for the identification of peptides and the mapping of proteomes. Over the …
Reversed‐phase chromatography with multiple fraction concatenation strategy for proteome profiling of human MCF10A cells
In this study, we evaluated a concatenated low pH (pH 3) and high pH (pH 10) reversed‐
phase liquid chromatography strategy as a first dimension for two‐dimensional liquid …
phase liquid chromatography strategy as a first dimension for two‐dimensional liquid …
[HTML][HTML] Full dynamic range proteome analysis of S. cerevisiae by targeted proteomics
The rise of systems biology implied a growing demand for highly sensitive techniques for the
fast and consistent detection and quantification of target sets of proteins across multiple …
fast and consistent detection and quantification of target sets of proteins across multiple …
Analysis and validation of proteomic data generated by tandem mass spectrometry
The analysis of the large amount of data generated in mass spectrometry–based proteomics
experiments represents a significant challenge and is currently a bottleneck in many …
experiments represents a significant challenge and is currently a bottleneck in many …
High-pH reversed-phase chromatography with fraction concatenation for 2D proteomic analysis
Orthogonal high-resolution separations are critical for attaining improved analytical dynamic
range and protein coverage in proteomic measurements. High-pH reversed-phase liquid …
range and protein coverage in proteomic measurements. High-pH reversed-phase liquid …