Mitochondrial membrane lipids in the regulation of bioenergetic flux
Oxidative phosphorylation (OXPHOS) occurs through and across the inner mitochondrial
membrane (IMM). Mitochondrial membranes contain a distinct lipid composition, aided by …
membrane (IMM). Mitochondrial membranes contain a distinct lipid composition, aided by …
Review of eukaryote cellular membrane lipid Composition, with special attention to the fatty acids
Biological membranes, primarily composed of lipids, envelop each living cell. The intricate
composition and organization of membrane lipids, including the variety of fatty acids they …
composition and organization of membrane lipids, including the variety of fatty acids they …
Intermittent glucocorticoid treatment enhances skeletal muscle performance through sexually dimorphic mechanisms
IM Salamone, M Quattrocelli… - The Journal of …, 2022 - Am Soc Clin Investig
Glucocorticoid steroids are commonly prescribed for many inflammatory conditions, but
chronic daily use produces adverse effects, including muscle wasting and weakness. In …
chronic daily use produces adverse effects, including muscle wasting and weakness. In …
Loss of Mitochondrial Ca2+ Uniporter Limits Inotropic Reserve and Provides Trigger and Substrate for Arrhythmias in Barth Syndrome Cardiomyopathy
Background: Barth syndrome (BTHS) is caused by mutations of the gene encoding tafazzin,
which catalyzes maturation of mitochondrial cardiolipin and often manifests with systolic …
which catalyzes maturation of mitochondrial cardiolipin and often manifests with systolic …
Reign in the membrane: How common lipids govern mitochondrial function
The lipids that make up biological membranes tend to be the forgotten molecules of cell
biology. The paucity of data on these important entities likely reflects the difficulties of …
biology. The paucity of data on these important entities likely reflects the difficulties of …
[HTML][HTML] Oxidative damage in the gastrocnemius of patients with peripheral artery disease is myofiber type selective
P Koutakis, DJ Weiss, D Miserlis, VK Shostrom… - Redox biology, 2014 - Elsevier
Background Peripheral artery disease (PAD), a manifestation of systemic atherosclerosis
that produces blockages in the arteries supplying the legs, affects approximately 5% of …
that produces blockages in the arteries supplying the legs, affects approximately 5% of …
Multimodal high-resolution nano-DESI MSI and immunofluorescence imaging reveal molecular signatures of skeletal muscle fiber types
The skeletal muscle is a highly heterogeneous tissue comprised of different fiber types with
varying contractile and metabolic properties. The complexity in the analysis of skeletal …
varying contractile and metabolic properties. The complexity in the analysis of skeletal …
[HTML][HTML] Understanding tumor anabolism and patient catabolism in cancer-associated cachexia
A Schcolnik-Cabrera, A Chávez-Blanco… - American journal of …, 2017 - ncbi.nlm.nih.gov
Cachexia is a multifactorial paraneoplastic syndrome commonly associated with advanced
stages of cancer. Cachexia is responsible for poor responses to antitumoral treatment and …
stages of cancer. Cachexia is responsible for poor responses to antitumoral treatment and …
The mitochondrial transacylase, tafazzin, regulates AML stemness by modulating intracellular levels of phospholipids
Tafazzin (TAZ) is a mitochondrial transacylase that remodels the mitochondrial cardiolipin
into its mature form. Through a CRISPR screen, we identified TAZ as necessary for the …
into its mature form. Through a CRISPR screen, we identified TAZ as necessary for the …
Incorporation of omega-3 fatty acids into human skeletal muscle sarcolemmal and mitochondrial membranes following 12 weeks of fish oil supplementation
CJ Gerling, K Mukai, A Chabowski… - Frontiers in …, 2019 - frontiersin.org
Fish oil (FO) supplementation in humans results in the incorporation of omega-3 fatty acids
(FAs) eicosapentaenoic acid (EPA; C20: 5) and docosahexaenoic acid (DHA; C20: 6) into …
(FAs) eicosapentaenoic acid (EPA; C20: 5) and docosahexaenoic acid (DHA; C20: 6) into …