Scaffolding biomaterials for 3D cultivated meat: prospects and challenges

C Bomkamp, SC Skaalure, GF Fernando… - Advanced …, 2022 - Wiley Online Library
Cultivating meat from stem cells rather than by raising animals is a promising solution to
concerns about the negative externalities of meat production. For cultivated meat to fully …

[HTML][HTML] Bioactive peptides for boosting stem cell culture platform: Methods and applications

AA Dayem, SB Lee, KM Lim, A Kim, HJ Shin… - Biomedicine & …, 2023 - Elsevier
Peptides, short protein fragments, can emulate the functions of their full-length native
counterparts. Peptides are considered potent recombinant protein alternatives due to their …

[HTML][HTML] Mechanistic insights into the adsorption and bioactivity of fibronectin on surfaces with varying chemistries by a combination of experimental strategies and …

L Hao, T Li, L Wang, X Shi, Y Fan, C Du, Y Wang - Bioactive Materials, 2021 - Elsevier
Fibronectin (Fn) is significant to the performance of biomaterials, and the chemistry of
biomaterial surface play important roles in Fn adsorption and subsequent cell behavior …

Nanoparticles traversing the extracellular matrix induce biophysical perturbation of fibronectin depicted by surface chemistry

X Guo, L Yang, C Deng, L Ren, S Li, X Zhang, J Zhao… - Nanoscale, 2024 - pubs.rsc.org
While the filtering and accumulation effects of the extracellular matrix (ECM) on
nanoparticles (NPs) have been experimentally observed, the detailed interactions between …

Design of chemically defined synthetic substrate surfaces for the in vitro maintenance of human pluripotent stem cells: A review

P Zhou, L Qin, Z Ge, B Xie, H Huang… - … Research Part B …, 2022 - Wiley Online Library
Human pluripotent stem cells (hPSCs) have the potential of long‐term self‐renewal and
differentiation into nearly all cell types in vitro. Prior to the downstream applications, the …

[HTML][HTML] A Novel Recombinant Vitronectin Variant Supports the Expansion and Differentiation of Pluripotent Stem Cells in Defined Animal-Free Workflows

X Lu, E Perr, T Naqvi, D Galitz, M Andersen… - Cells, 2024 - pmc.ncbi.nlm.nih.gov
An essential aspect of harnessing the potential of pluripotent stem cells (PSCs) and their
derivatives for regenerative medicine is the development of animal-free and chemically …

[HTML][HTML] Efficient improvement of the proliferation, differentiation, and anti-arthritic capacity of mesenchymal stem cells by simply culturing on the immobilized FGF2 …

SB Lee, AA Dayem, S Kmiecik, KM Lim, DS Seo… - Journal of Advanced …, 2024 - Elsevier
Introduction The stem cell microenvironment has been evidenced to robustly affect its
biological functions and clinical grade. Natural or synthetic growth factors, especially, are …

Long‐Term Culture of Human Pluripotent Stem Cells in Xeno‐Free Condition Using Functional Polymer Films

Y Cho, H Lee, W Jeong, KB Jung, SY Lee… - Advanced …, 2024 - Wiley Online Library
Human pluripotent stem cells (hPSCs), encompassing human embryonic stem cells (hESCs)
and human induced pluripotent stem cells (hiPSCs), hold immense potential in regenerative …

Polymerized laminin-521: A feasible substrate for expanding induced pluripotent stem cells at a low protein concentration

FCP Mesquita, ES Leite, J Morrissey, C Freitas… - Cells, 2022 - mdpi.com
Laminins (LNs) play a central role in the self-assembly and maintenance of basement
membranes and are involved in critical interactions between cells and other extracellular …

Cell-binding peptides on the material surface guide stem cell fate of adhesion, proliferation and differentiation

TC Sung, T Wang, Q Liu, QD Ling… - Journal of Materials …, 2023 - pubs.rsc.org
Human cells, especially stem cells, need to communicate and interact with extracellular
matrix (ECM) proteins, which not only serve as structural components but also guide and …