Changing epidemiology of hepatocellular carcinoma in Asia

C Zhang, Y Cheng, S Zhang, J Fan, Q Gao - Liver International, 2022 - Wiley Online Library
Liver cancer is the fifth most common cancer and the second leading cause of malignant
death in Asia, and Asia reports 72.5% of the world's cases in 2020. As the most common …

The global epidemiology of NAFLD and NASH in patients with type 2 diabetes: a systematic review and meta-analysis

ZM Younossi, P Golabi, L de Avila, JM Paik… - Journal of …, 2019 - Elsevier
Background & Aims Although non-alcoholic fatty liver disease (NAFLD), non-alcoholic
steatohepatitis (NASH) and NASH with advanced fibrosis are closely associated with type 2 …

Molecular phenomics and metagenomics of hepatic steatosis in non-diabetic obese women

L Hoyles, JM Fernández-Real, M Federici, M Serino… - Nature medicine, 2018 - nature.com
Hepatic steatosis is a multifactorial condition that is often observed in obese patients and is
a prelude to non-alcoholic fatty liver disease. Here, we combine shotgun sequencing of fecal …

[PDF][PDF] Diagnostic modalities for nonalcoholic fatty liver disease, nonalcoholic steatohepatitis, and associated fibrosis

ZM Younossi, R Loomba, QM Anstee, ME Rinella… - …, 2018 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) is a spectrum comprised of isolated steatosis,
nonalcoholic steatohepatitis (NASH), advanced fibrosis, and cirrhosis. The majority of …

[PDF][PDF] Current and future therapeutic regimens for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

ZM Younossi, R Loomba, ME Rinella, E Bugianesi… - …, 2018 - Wiley Online Library
Nonalcoholic fatty liver disease (NAFLD) and its progressive form non‐alcoholic
steatohepatitis (NASH), are rapidly becoming among the top causes of cirrhosis …

Nonalcoholic fatty liver disease in adults: current concepts in etiology, outcomes, and management

T Marjot, A Moolla, JF Cobbold, L Hodson… - Endocrine …, 2020 - academic.oup.com
Nonalcoholic fatty liver disease (NAFLD) is a spectrum of disease, extending from simple
steatosis to inflammation and fibrosis with a significant risk for the development of cirrhosis. It …

[HTML][HTML] Treatment options for alcoholic and non-alcoholic fatty liver disease: A review

S Singh, NA Osna, KK Kharbanda - World journal of …, 2017 - ncbi.nlm.nih.gov
Alcoholic liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD) are serious
health problems worldwide. These two diseases have similar pathological spectra, ranging …

Nonalcoholic fatty liver disease progression rates to cirrhosis and progression of cirrhosis to decompensation and mortality: a real world analysis of Medicare data

R Loomba, R Wong, J Fraysse, S Shreay… - Alimentary …, 2020 - Wiley Online Library
Background Risk factors and timing associated with disease progression and mortality in
nonalcoholic fatty liver disease (NAFLD) are poorly understood. Aims To evaluate the impact …

The role of growth hormone and insulin-like growth factor-I in the liver

Y Takahashi - International journal of molecular sciences, 2017 - mdpi.com
Adult growth hormone deficiency (GHD) is characterized by metabolic abnormalities
associated with visceral obesity, impaired quality of life, and increased mortality. Patients …

[HTML][HTML] Pathophysiological mechanisms and clinical evidence of relationship between Nonalcoholic fatty liver disease (NAFLD) and cardiovascular disease

R Galiero, A Caturano, E Vetrano, A Cesaro… - Reviews in …, 2021 - imrpress.com
Evidence suggests a close connection between Nonalcoholic Fatty Liver Disease (NAFLD)
and increased cardiovascular (CV) risk. Several cross-sectional studies report that NAFLD is …