Insights into the Relationship between Pentraxin-3 and Cancer

M Bogdan, AD Meca, A Turcu-Stiolica… - International Journal of …, 2022 - mdpi.com
Although cancer can be cured if detected early and treated effectively, it is still a leading
cause of death worldwide. Tumor development can be limited by an appropiate immune …

Soluble Human Lectins at the Host–Microbe Interface

AL Peiffer, AE Dugan… - Annual Review of …, 2024 - annualreviews.org
Human lectins are integral to maintaining microbial homeostasis on the skin, in the blood,
and at mucosal barriers. These proteins can recognize microbial glycans and inform the host …

Pentraxin 3 exacerbates psoriasiform dermatitis through regulation of macrophage polarization

J Liu, C Qiu, Z Zhou, J Li, Y Zhen, R Wang… - International …, 2024 - Elsevier
Objective To elucidate the mechanism of Pentraxin 3 (PTX3) in the pathogenesis of
psoriasiform dermatitis using Ptx3-knockout (Ptx3-KO) background mice. Methods An …

Functional variants of the pentraxin 3 gene are associated with the metastasis and progression of prostate cancer

WC Weng, YH Hsieh, CY Lin, YF Liu… - Journal of Cellular …, 2024 - Wiley Online Library
Age, ethnic background and genetic components have been identified as the established
risks for prostate cancer (PCa). Pentraxin 3 (PTX3), originally identified as a pattern …

Immunomodulatory Effect of Hypericin-Mediated Photodynamic Therapy on Oral Cancer Cells

M Olek, A Machorowska-Pieniążek, ZP Czuba… - Pharmaceutics, 2023 - mdpi.com
In 2020, there were 377,713 new oral and lip cancer diagnoses and 177,757 deaths. Oral
cancer is a malignancy of the head and neck region, and 90% of cases are squamous cell …

The pentraxin family in autoimmune disease

Y Li, S Zhang, J Liu, Y Zhang, N Zhang, Q Cheng… - Clinica Chimica …, 2023 - Elsevier
The pentraxins represent a family of multifunctional proteins composed of long and short
pentamers. The latter includes serum amyloid P component (SAP) and C-reactive protein …

Markers of extracellular matrix remodeling and systemic inflammation in patients with heritable thoracic aortic diseases

BE Seim, MF Holt, A Ratajska, A Michelsen… - Frontiers in …, 2022 - frontiersin.org
Background In approximately 20% of patients with thoracic aortic aneurysms or dissections
a heritable thoracic aortic disease (HTAD) is suspected. Several monogenic connective …

Pentraxin 3: A Main Driver of Inflammation and Immune System Dysfunction in the Tumor Microenvironment of Glioblastoma

SA Scuderi, A Ardizzone, AE Salako, G Pantò… - Cancers, 2024 - mdpi.com
Simple Summary Brain tumors, including glioblastoma (GB), pose a significant health
concern globally, with high mortality rates despite current therapies. Pentraxin 3 (PTX3) is a …

Assessing the Inhibitory Potential of Pregnenolone Sulfate on Pentraxin 3 in Diabetic Kidney Disease: A Molecular Docking and Simulation Study

S Das, G Ramanathan - Journal of Cellular Biochemistry, 2024 - Wiley Online Library
ABSTRACT Diabetic Kidney Disease (DKD), a frequent consequence of diabetes, has
substantial implications for both morbidity and mortality rates, prompting the exploration of …

Deciphering the Role of SLFN12: A Novel Biomarker for Predicting Immunotherapy Outcomes in Glioma Patients Through Artificial Intelligence

Z Chen, C Liu, W Zheng, Y Fang… - Journal of Cellular …, 2024 - Wiley Online Library
Gliomas are the most prevalent form of primary brain tumours. Recently, targeting the PD‐1
pathway with immunotherapies has shown promise as a novel glioma treatment. However …