LINE-1 elements in structural variation and disease

CR Beck, JL Garcia-Perez, RM Badge… - Annual review of …, 2011 - annualreviews.org
The completion of the human genome reference sequence ushered in a new era for the
study and discovery of human transposable elements. It now is undeniable that …

[HTML][HTML] PiggyBac transposon vectors: the tools of the human gene encoding

S Zhao, E Jiang, S Chen, Y Gu… - … lung cancer research, 2016 - ncbi.nlm.nih.gov
A transposon is a DNA segment, which is able to change its relative position within the entire
genome of a cell. The piggyBac (PB) transposon is a movable genetic element that …

A review of current large‐scale mouse knockout efforts

C Guan, C Ye, X Yang, J Gao - genesis, 2010 - Wiley Online Library
After the successful completion of the human genome project (HGP), biological research in
the postgenome era urgently needs an efficient approach for functional analysis of genes …

Potential friend recommendation in online social network

X Xie - 2010 IEEE/ACM Int'l Conference on Green Computing …, 2010 - ieeexplore.ieee.org
As the wide popularization of online social networks, online users are not content only with
keeping online friendship with social friends in real life any more. They hope the system …

Towards systematic functional characterization of cancer genomes

JS Boehm, WC Hahn - Nature Reviews Genetics, 2011 - nature.com
Whole-genome approaches to identify genetic and epigenetic alterations in cancer
genomes have begun to provide new insights into the range of molecular events that occurs …

Trends in large-scale mouse mutagenesis: from genetics to functional genomics

Y Gondo - Nature Reviews Genetics, 2008 - nature.com
The primary goal of mouse mutagenesis programmes is to develop a fundamental research
infrastructure for mammalian functional genomics and to produce human disease models …

An miRNA-mRNA integrative analysis in human placentas and mice: role of the Smad2/miR-155-5p axis in the development of fetal growth restriction

JX Wu, M Shi, BM Gong, BW Ji, CC Hu… - … in Bioengineering and …, 2023 - frontiersin.org
Introduction: Functional disorder of the placenta is the principal cause of fetal growth
restriction (FGR), usually cured with suitable clinical treatment and good nursing. However …

Genome walking in eukaryotes

C Leoni, M Volpicella, F De Leo, R Gallerani… - The FEBS …, 2011 - Wiley Online Library
Genome walking is a molecular procedure for the direct identification of nucleotide
sequences from purified genomes. The only requirement is the availability of a known …

[HTML][HTML] Cytosolic carboxypeptidase CCP6 is required for megakaryopoiesis by modulating Mad2 polyglutamylation

B Ye, C Li, Z Yang, Y Wang, J Hao, L Wang… - The Journal of …, 2014 - ncbi.nlm.nih.gov
Bone marrow progenitor cells develop into mature megakaryocytes (MKs) to produce
platelets for hemostasis and other physiological functions. However, the molecular …

The mouse genetics toolkit: revealing function and mechanism

L Van der Weyden, JK White, DJ Adams, DW Logan - Genome biology, 2011 - Springer
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