Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite
accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite …

Lipid encapsulated messenger RNA (LNP mRNA) has garnered a significant amount of
interest from the pharmaceutical industry and general public alike. This attention has been …

The development of novel electrocatalyst materials with excellent characteristics is inevitably
needed to satisfy the practical application of electrochemical sensors. In this study, the 2D …

Resolving inflammation and promoting intestinal tissue regeneration are critical for
inflammatory bowel disease (IBD) treatment. Bioactive glass (BG) is a clinically approved …

Purpose Ulcerative colitis (UC) is a chronic inflammatory bowel disease that starts with
mucosal inflammation of the rectum and extends proximally in the colon in a continuous …

Lipid homeostasis is considered to be related to intestinal metabolic balance, while its role
in the pathogenesis and treatment of ulcerative colitis (UC) remains largely unexplored. The …

Liver fibrosis is characterized by the abnormal deposition of the extracellular matrix with a
severe inflammatory response and/or metabolic disorder. Asiatic acid (AA), a natural …

Protopanaxadiol (PPD) has potential immunomodulatory effects, but the underlying
mechanism remains unclear. Here, we explored the potential roles of gut microbiota in the …

Bioactive peptides exhibit key roles in a wide variety of complex processes, such as
regulation of body weight, learning, aging, and innate immune response. Next to the …

Sepsis usually leads to lethal multiorgan dysfunction including acute liver failure (ALF) and
acute lung injury (ALI). This research sought to reveal the lipid alteration of anti-high mobility …