HIV-exposed, uninfected infants: new global challenges in the era of paediatric HIV elimination

C Evans, CE Jones, AJ Prendergast - The Lancet infectious diseases, 2016 - thelancet.com
The number of infants infected with HIV is declining with the rise in interventions for the
elimination of paediatric HIV infection, but the number of uninfected infants exposed to HIV …

Growth and neurodevelopment of HIV-exposed uninfected children: a conceptual framework

CJ Wedderburn, C Evans, S Yeung, DM Gibb… - Current HIV/AIDS …, 2019 - Springer
Abstract Purpose of Review The population of HIV-exposed uninfected (HEU) children is
expanding rapidly, and over one million HEU infants are born each year globally. Several …

Pattern of infectious morbidity in HIV-exposed uninfected infants and children

AL Slogrove, T Goetghebuer, MF Cotton… - Frontiers in …, 2016 - frontiersin.org
Background Almost 30% of children in Southern Africa are HIV exposed but uninfected
(HEU) and experience exposures that could increase vulnerability to infectious diseases …

Maternal HIV infection influences the microbiome of HIV-uninfected infants

JM Bender, F Li, S Martelly, E Byrt, V Rouzier… - Science translational …, 2016 - science.org
More than 1 million HIV-exposed, uninfected infants are born annually to HIV-positive
mothers worldwide. This growing population of infants experiences twice the mortality of HIV …

Epidemiology of acute lower respiratory tract infection in HIV-exposed uninfected infants

C Cohen, J Moyes, S Tempia, M Groome… - …, 2016 - publications.aap.org
BACKGROUND: Increased morbidity and mortality from lower respiratory tract infection
(LRTI) has been suggested in HIV-exposed uninfected (HEU) children; however, the …

[PDF][PDF] British HIV Association guidelines for the management of HIV in pregnancy and postpartum 2018

Y Gilleece, S Tariq, A Bamford, S Bhagani… - HIV …, 2019 - discovery.ucl.ac.uk
A key goal of managing HIV in pregnancy and postpartum is to optimise a woman's own
health. Furthermore, one of the major successes in the management of individuals living …

Increased risk for and mortality from invasive pneumococcal disease in HIV-exposed but uninfected infants aged< 1 year in South Africa, 2009–2013

C Von Mollendorf, A Von Gottberg… - Clinical Infectious …, 2015 - academic.oup.com
Background. High antenatal human immunodeficiency virus (HIV) seroprevalence rates (∼
30%) with low perinatal HIV transmission rates (2.5%), due to HIV prevention of mother-to …

Initiation of antiretroviral therapy before pregnancy reduces the risk of infection-related hospitalization in human immunodeficiency virus–exposed uninfected infants …

T Goetghebuer, KK Smolen, C Adler… - Clinical infectious …, 2019 - academic.oup.com
Background Epidemiological studies conducted in low-and high-income countries showed
that infants exposed to maternal human immunodeficiency virus (HIV) have a high risk of …

Increased infectious-cause hospitalization among infants who are HIV-exposed uninfected compared with HIV-unexposed

K Anderson, E Kalk, HP Madlala, DC Nyemba… - Aids, 2021 - journals.lww.com
Objectives: Increased risk of morbidity and hospitalization has been observed in children
who are HIV-exposed uninfected (HEU) compared with HIV-unexposed uninfected (HUU) …

Evolution of the gut microbiome in HIV-exposed uninfected and unexposed infants during the first year of life

CL Jackson, DN Frank, CE Robertson, D Ir… - Mbio, 2022 - Am Soc Microbiol
ABSTRACT HIV-exposed uninfected infants (HEU) have abnormal immunologic functions
and increased infectious morbidity in the first 6 months of life, which gradually decreases …