Since their discovery over 100 years ago cyclodextrins (CDs) have been the subject of
numerous scientific publications. In 2016 alone CDs were the subject of over 2200 research …

Dry eye disease (DED) is a frequently observed eye complaint, which has recently attracted
considerable research interest. Conventional therapy for DED involves the use of artificial …

Cyclodextrin (CD), a class of cyclic oligosaccharides with an external hydrophilic surface
and a central hydrophobic cavity is recognized as a promising pharmaceutical excipient due …

Ocular diseases may be treated via different routes of administration, such as topical,
intracameral, intravitreal, oral and parenteral. Among them the topical route is most accepted …

Cyclodextrins (CDs) have been widely investigated as a unique pharmaceutical excipient for
past few decades and is still explored for new applications. They are highly versatile …

Most dry eye syndromes (DES) are caused by oxidative stress and an overactive
inflammatory response, leading to tear deficiency and excessive tear evaporation …

Colloidal nanoparticulate technology has been described in the literature as a versatile drug
delivery system. But it possesses some inherent lacunae in their formulation. Cyclodextrins …

Cyclodextrins (CDs) are widely used in pharmaceutical products for improving the solubility
and bioavailability of drugs through the formation of water-soluble inclusion complexes …

The aim of this work was to design and evaluate novel cationized hyaluronic acid coated
spanlastics (CHASVs), with the immunosuppressive peptide cyclosporine A (CsA) as the …

Ocular drug delivery presents a unique set of challenges owing to the complex anatomy and
physiology of the eye. Processed excipients have emerged as crucial components in …