A comprehensive review of pathological mechanisms and natural dietary ingredients for the management and prevention of sarcopenia

J Kim, JY Lee, CY Kim - Nutrients, 2023 - mdpi.com
Sarcopenia is characterized by an age-related loss of skeletal muscle mass and function
and has been recognized as a clinical disease by the World Health Organization since …

A novel treatment strategy targeting cellular pathways with natural products to alleviate sarcopenia

DH Lee, HJ Lee, G Yang, DY Kim, JU Kim… - Phytotherapy …, 2024 - Wiley Online Library
Sarcopenia is a condition marked by a significant reduction in muscle mass and strength,
primarily due to the aging process, which critically impacts muscle protein dynamics …

Therapeutic roles of plants for 15 hypothesised causal bases of Alzheimer's disease

SEB Tyler, LDK Tyler - Natural Products and Bioprospecting, 2022 - Springer
Alzheimer's disease (AD) is progressive and ultimately fatal, with current drugs failing to
reverse and cure it. This study aimed to find plant species which may provide therapeutic …

KYMASIN UP natural product inhibits osteoclastogenesis and improves osteoblast activity by modulating Src and p38 MAPK

L Salvadori, ML Belladonna, B Castiglioni, M Paiella… - Nutrients, 2022 - mdpi.com
The imbalance in osteoblast (OB)-dependent bone formation in favor of osteoclast (OC)-
dependent bone resorption is the main cause of loss of tissue mineral mass during bone …

[HTML][HTML] Equisetum arvense standardized dried extract hinders age-related osteosarcopenia

L Salvadori, M Paiella, B Castiglioni… - Biomedicine & …, 2024 - Elsevier
Age-associated osteosarcopenia is an unresolved syndrome characterized by the
concomitant loss of bone (osteopenia) and skeletal muscle (sarcopenia) tissues increasing …

Frailty in kidney transplant candidates and recipients: pathogenesis and intervention strategies

H Cao, J Zhang, Z Sun, J Wu, C Hao… - Chinese Medical …, 2023 - mednexus.org
With the rapid aging of the global population posing a serious problem, frailty, a non-specific
state that reflects physiological senescence rather than aging in time, has become more …

Emerging Vistas for the Nutraceutical Withania somnifera in Inflammaging

V Basudkar, G Gujrati, S Ajgaonkar, M Gandhi… - Pharmaceuticals, 2024 - mdpi.com
Inflammaging, a coexistence of inflammation and aging, is a persistent, systemic, low-grade
inflammation seen in the geriatric population. Various natural compounds have been greatly …

Protective Role of Ethanol Extract of Cibotium barometz (Cibotium Rhizome) against Dexamethasone-Induced Muscle Atrophy in C2C12 Myotubes

NH Kim, JY Lee, CY Kim - International Journal of Molecular Sciences, 2023 - mdpi.com
Sarcopenia is a progressive muscle disease characterized by the loss of skeletal muscle
mass, strength, function, and physical performance. Since the disease code was assigned …

[PDF][PDF] Promising therapeutic efficacy of Trigonella-foenum graecum and bone marrow-derived mesenchymal stem cells on skeletal muscle atrophy in experimental rat …

HE Abd El Aty, AM Zaazaa… - … Res Appl Chem, 2023 - biointerfaceresearch.com
Skeletal muscle plasticity is maintained by various ways to regulate cell and protein
turnover. When muscle atrophy occurs, proteolytic cascades are activated, resulting in the …

Sertoli cells improve myogenic differentiation, reduce fibrogenic markers, and induce utrophin expression in human DMD myoblasts

L Salvadori, S Chiappalupi, I Arato, F Mancuso… - Biomolecules, 2021 - mdpi.com
Duchenne muscular dystrophy (DMD) is an X-linked disease caused by mutations in DMD
gene translating in lack of functional dystrophin and resulting in susceptibility of myofibers to …