Publisher Summary Oligonucleotide-directed mutagenesis is a widely used procedure for
studying the structure and function of DNA and the macromolecules for which it codes. The …

Resistance to copper's toxicity in yeast is controlled by the CUP1r locus. This gene was
cloned by transforming sensitive recipients (cup1 (8)) with a collection of hybrid DNA …

Inflammatory diseases of the gastrointestinal tract are frequently associated with
dysbiosis,,,,,,,, characterized by changes in gut microbial communities that include an …

Changes in the microbial community structure are observed in individuals with intestinal
inflammatory disorders. These changes are often characterized by a depletion of obligate …

We have developed a new vector strategy for the insertion of foreign genes into the
genomes of gram negative bacteria not closely related to Escherichia coli. The system …

Salmonella enterica serotype Typhimurium (S. Typhimurium) causes acute gut inflammation
by using its virulence factors to invade the intestinal epithelium and survive in mucosal …

Conventional wisdom holds that microbes support their growth in vertebrate hosts by
exploiting a large variety of nutrients. We show here that use of a specific nutrient …

A gene bank of Sau 3A partially digested Candida albicans DNA in vector YEp13 was used
to complement a ura3 mutation (orotidine-5′-phosphate decarboxylase, OMPdecase) in S …

cagA, a gene that codes for an immunodominant antigen, is present only in Helicobacter
pylori strains that are associated with severe forms of gastroduodenal disease (type I …

Human color vision is based on three light-sensitive pigments. The isolation and sequencing
of genomic and complementary DNA clones that encode the apoproteins of these three …