This clinical review explored coagulopathy in severely bleeding patients after major surgery
(eg, cardiac surgery with cardiopulmonary bypass or CPB), serious trauma, and postpartum …

Disseminated intravascular coagulation (DIC) has been understood as a consumptive
coagulopathy. However, impaired hemostasis is a component of DIC that occurs in a …

Trauma is a leading cause of death and morbidity worldwide. Here, we present the analysis
of a longitudinal multi-omic dataset comprising clinical, cytokine, endotheliopathy biomarker …

The coronavirus disease 2019 (COVID-19), first identified in December 2019 in Wuhan,
China, is a major public health crisis with new infections increasing exponentially worldwide …

Disseminated intravascular coagulation (DIC) is not a disease criterion but a
pathomechanistic process that accompanies various underlying diseases. According to the …

Background Trauma‐induced coagulopathy (TIC) may progress to disseminated
intravascular coagulation (DIC) due to dysregulated inflammatory and coagulofibrinolytic …

Tranexamic acid (TXA) is an antifibrinolytic agent originally developed for the management
of bleeding in the setting of postpartum hemorrhage (PPH). Over the last 15 years, there has …

Deranged Balance of Hemostasis and Fibrinolysis in Disseminated Intravascular Coagulation:
Assessment and Relevance in Different Clinical Settings Deranged Balance of Hemostasis and …

Introduction Recently, clot-fibrinolysis waveform analysis (CFWA), which is a coagulation
and fibrinolysis global assay based on assessing the activated partial thromboplastin time …

Trauma-induced coagulopathy (TIC) is caused by post-traumatic tissue injury and manifests
as hypercoagulability that leads to thromboembolism or hypocoagulability that leads to …