Exploring the Biological Pathways of Siderophores and Their Multidisciplinary Applications: A Comprehensive Review

B Xie, X Wei, C Wan, W Zhao, R Song, S Xin, K Song - Molecules, 2024 - mdpi.com
Siderophores are a class of small molecules renowned for their high iron binding capacity,
essential for all life forms requiring iron. This article provides a detailed review of the diverse …

Structures of the mycobacterial MmpL4 and MmpL5 transporters provide insights into their role in siderophore export and iron acquisition

R Maharjan, Z Zhang, PA Klenotic, WD Gregor… - Plos …, 2024 - journals.plos.org
The Mycobacterium tuberculosis (Mtb) pathogen, the causative agent of the airborne
infection tuberculosis (TB), harbors a number of mycobacterial membrane protein large …

Stealing Survival: Iron Acquisition Strategies of Mycobacterium tuberculosis

G Shankar, Y Akhter - Biochimie, 2024 - Elsevier
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), faces iron
scarcity within the host due to immune defenses. This review explores the importance of iron …

Liposome-siderophore conjugates loaded with moxifloxacin serve as a model for drug delivery against Mycobacterium tuberculosis

CM Ribeiro, CA Roque-Borda, MC Franzini… - International Journal of …, 2024 - Elsevier
Tuberculosis (TB) is an infectious disease that annually affects millions of people, and
resistance to available antibiotics has exacerbated this situation. Another notable …

The structure of Mycobacterium thermoresistibile MmpS5 reveals a conserved disulfide bond across mycobacteria

BJ Cuthbert, J Mendoza, R de Miranda… - Metallomics, 2024 - academic.oup.com
The tuberculosis (TB) emergency has been a pressing health threat for decades. With the
emergence of drug-resistant TB and complications from the COVID-19 pandemic, the TB …

Global prevalence of Mycobacterium massiliense strains with recombinant rpoB genes (Rec-Mas) horizontally transferred from Mycobacterium abscessus: two …

DH Kim, H Seo, S Jung, BJ Kim - Microbiology Spectrum, 2024 - journals.asm.org
Mycobacterium abscessus is a group of emerging antimicrobial-resistant nontuberculous
mycobacteria that causes severe lung disease in infected patients globally. Recently …

[HTML][HTML] 结核分枝杆菌耐药机制的研究进展

庞佳琦, 郑改焕 - Advances in Clinical Medicine, 2024 - hanspub.org
结核病(Tuberculosis, TB) 是由结核分枝杆菌(Mycobacterium tuberculosis, MTB)
引发的慢性传染病, 不仅有极高的致死性, 更是全球公共卫生领域所面临的巨大挑战 …

Netupitant Exhibits Potent Activity on Mycobacterium tuberculosis Persisters

HE Eldesouky, RM Jones, N Gleason, S Mohammed… - bioRxiv, 2024 - biorxiv.org
In Mycobacterium tuberculosis (Mtb), persisters are genotypically drug-sensitive bacteria
that nonetheless survive antibiotic treatment. Persisters represent a significant challenge to …

Multidrug efflux pumps of Pseudomonas aeruginosa show selectivity for their natural substrates

L Mazza, A Bory, A Luscher, J Kloehn, W Jean-Luc… - Frontiers in … - frontiersin.org
Antibiotic-resistant Gram-negative bacteria are an increasing threat to human health.
Strategies to restore antibiotic efficacy include targeting multidrug efflux pumps by …