mRNA vaccines in tumor targeted therapy: Mechanism, clinical application, and development trends

Y Gao, L Yang, Z Li, X Peng, H Li - Biomarker Research, 2024 - Springer
Malignant tumors remain a primary cause of human mortality. Among the various treatment
modalities for neoplasms, tumor vaccines have consistently shown efficacy and promising …

[HTML][HTML] The Triad of Sleep, Immunity, and Cancer: A Mediating Perspective

G Lanza, MP Mogavero, M Salemi, R Ferri - Cells, 2024 - mdpi.com
The triadic interplay between sleep, immunity, and cancer represents a growing area of
biomedical research with significant clinical implications. This review synthesizes the current …

Integrating single‐cell transcriptomics and machine learning to predict breast cancer prognosis: A study based on natural killer cell‐related genes

J Mao, L Liu, Q Shen, M Cen - Journal of Cellular and …, 2024 - Wiley Online Library
Breast cancer (BC) is the most commonly diagnosed cancer in women globally. Natural
killer (NK) cells play a vital role in tumour immunosurveillance. This study aimed to establish …

[HTML][HTML] Advancements in the Application of scRNA-Seq in Breast Research: A Review

Z Zhang, X Ma, Y La, X Guo, M Chu, P Bao… - International Journal of …, 2024 - mdpi.com
Single-cell sequencing technology provides apparent advantages in cell population
heterogeneity, allowing individuals to better comprehend tissues and organs. Sequencing …

Unlocking the Potential of CAR-NK Cell Therapy: Overcoming Barriers and Challenges in the Treatment of Myeloid Malignancies

A Zhang, X Yang, Y Zhang, X Yu, W Mu… - Molecular Cancer …, 2025 - aacrjournals.org
Myeloid malignancies include various types of cancers that arise from abnormal
development or proliferation of myeloid cells within the bone marrow. Chimeric antigen …

Innovative cell therapies for systemic sclerosis: available evidence and new perspectives

A Lescoat, M Ghosh, S Kadauke… - Expert Review of Clinical …, 2024 - Taylor & Francis
ABSTRACT Introduction Systemic sclerosis (SSc) is the rheumatic disease with the highest
individual mortality rate with a detrimental impact on quality of life. Cell-based therapies may …

Immune Biomarkers and Predictive Signatures in Gastric Cancer: Optimizing Immunotherapy Responses

V Sundaram, SS Infant, S Manikandan, DJ Rani… - … -Research and Practice, 2024 - Elsevier
Gastric cancer is a malignant disease with a poor prognosis and few therapeutic options
once it has advanced. Immunotherapy using ICIs has emerged as a viable therapeutic …

[HTML][HTML] Single-cell sequencing technology to characterize stem T-cell subpopulations in acute T-lymphoblastic leukemia and the role of stem T-cells in the disease …

Y Li, Z Jia, X Liu, H Zhao, G Cui, J Luo… - Aging (Albany …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Precursor T-cell acute lymphoblastic leukemia (Pre-T ALL) is a malignant
neoplastic disease in which T-cells proliferate in the bone marrow. Single-cell sequencing …

Efficient Design and Optimization of High-Speed Electronic System Interconnects Using Machine Learning Applications

A Saravanan, S Bathrinath, H Banda… - … and Optimization of …, 2024 - igi-global.com
This work presents a holistic framework for automating automated guided vehicles (AGVs) in
industrial settings by using well-positioned sensors and sophisticated machine learning …