Chikungunya virus (CHIKV) is currently one of the most relevant arboviruses to public
health. It is a member of the Togaviridae family and alphavirus genus and causes an …

Highlights•Drug repurposing is a powerful strategy for discovering new indications for drugs
that are used in various clinical applications.•The repurposing drugs approach reduces the …

Chikungunya virus (CHIKV) is the causative agent of Chikungunya fever, an acute febrile
and arthritogenic illness with no effective treatments available. The development of effective …

Most of the patients infected with Chikungunya virus (CHIKV) develop chronic
manifestations characterized by pain and deformity in joints, impacting their quality of life …

Chikungunya virus (CHIKV) is the causative agent of chikungunya fever, a disease that can
result in disability. Until now, there is no antiviral treatment against CHIKV, demonstrating …

Herein a systematic series of four [AuLL'] n+ n= 0,+ 1 complexes, where L= 1, 3-bis (mesityl)
imidazole-2-ylidene (IMes), or triphenylphosphine (PPh3), and L'= chloride, or 4 …

Background Currently, there is no antiviral licensed to treat chikungunya fever, a disease
caused by the infection with Alphavirus chikungunya (CHIKV). Treatment is based on …

Background Chikungunya fever is an endemic disease caused by the Chikungunya virus
(CHIKV). To date there is no antiviral treatment against this infection or licensed vaccine to …

Amantadine (AMA) is a useful drug in neuronal disorders, but few studies have been
performed to access its toxicological profile. Conversely, doxorubicin (Dox) is a well-known …

In this paper, we report the synthesis, structural characterization, and antiviral properties of
palladium (II) complexes with amantadine (atd) and memantine (mtn). Elemental and mass …