Design of hydrogel-based scaffolds for the treatment of spinal cord injuries

N Ghane, MH Beigi, S Labbaf… - Journal of Materials …, 2020 - pubs.rsc.org
Spinal cord injury (SCI) is a traumatic lesion that diminishes sensory and/or motor neuronal
functionality, directly affecting the quality of the patient's life. Due to the central nervous …

[HTML][HTML] Revealing an important role of piezoelectric polymers in nervous-tissue regeneration: a review

LE Shlapakova, MA Surmeneva, AL Kholkin… - Materials Today Bio, 2024 - Elsevier
Nerve injuries pose a drastic threat to nerve mobility and sensitivity and lead to permanent
dysfunction due to low regenerative capacity of mature neurons. The electrical stimuli that …

Functional self-assembling peptide nanofiber hydrogels designed for nerve degeneration

Y Sun, W Li, X Wu, N Zhang, Y Zhang… - … applied materials & …, 2016 - ACS Publications
Self-assembling peptide (SAP) RADA16-I (Ac-(RADA) 4-CONH2) has been suffering from a
main drawback associated with low pH, which damages cells and host tissues upon direct …

Microbial polyhydroxyalkanoates as medical implant biomaterials

GQ Chen, J Zhang - Artificial Cells, Nanomedicine, and …, 2018 - Taylor & Francis
Polyhydroxyalkanoates (PHAs), a diverse biopolyester synthesized by many bacteria as
intracellular carbon and energy storage materials, have been produced in large quantity for …

Elastomeric polyesters in cardiovascular tissue engineering and organs-on-a-chip

S Okhovatian, A Shakeri, L Davenport Huyer… - …, 2023 - ACS Publications
Cardiovascular tissue constructs provide unique design requirements due to their functional
responses to substrate mechanical properties and cyclic stretching behavior of cardiac …

Metabolically glycoengineered neural stem cells boost neural repair after cardiac arrest

J Du, X Liu, S Marasini, Z Wang… - Advanced Functional …, 2024 - Wiley Online Library
Cardiac arrest (CA)‐induced cerebral ischemia remains challenging with high mortality and
disability. Neural stem cell (NSC) engrafting is an emerging therapeutic strategy with …

Adding functions to biomaterial surfaces through protein incorporation

MA Wronska, IB O'Connor, MA Tilbury… - Advanced …, 2016 - Wiley Online Library
The concept of biomaterials has evolved from one of inert mechanical supports with a long‐
term, biologically inactive role in the body into complex matrices that exhibit selective cell …

Extracellular matrix components in peripheral nerve repair: how to affect neural cellular response and nerve regeneration?

AC De Luca, SP Lacour, W Raffoul… - Neural regeneration …, 2014 - journals.lww.com
Peripheral nerve injury is a serious problem affecting significantly patients' life. Autografts
are the “gold standard” used to repair the injury gap, however, only 50% of patients fully …

Noncovalent bonding of RGD and YIGSR to an electrospun poly (ε‐caprolactone) conduit through peptide self‐assembly to synergistically promote sciatic nerve …

L Zhu, K Wang, T Ma, L Huang, B Xia… - Advanced …, 2017 - Wiley Online Library
The nerve conduit with biofunctionalities can regulate neurite outgrowth, as well as the
migration, proliferation, and myelination activity of Schwann cells. In the present study …

Poly (3-hydroxybutyrate-co-3-hydroxyvalerate-co-3-hydroxyhexanoate) terpolymer production from volatile fatty acids using engineered Ralstonia eutropha

HR Jung, JM Jeon, DH Yi, HS Song, SY Yang… - International journal of …, 2019 - Elsevier
One of the advantages of microbial synthesis of polyhydroxyalkanoates (PHAs) is the
production of diverse polymers with different properties by the addition of different …