The link between the gut microbiome, inflammation, and Parkinson's disease

S Nie, Y Ge - Applied Microbiology and Biotechnology, 2023 - Springer
As our society ages, the growing number of people with Parkinson's disease (PD) puts
tremendous pressure on our society. Currently, there is no effective treatment for PD, so …

Hydrogen sulfide signalling in neurodegenerative diseases

SJ Tripathi, S Chakraborty, E Miller… - British Journal of …, 2023 - Wiley Online Library
The gaseous neurotransmitter hydrogen sulfide (H2S) exerts neuroprotective efficacy in the
brain via post‐translational modification of cysteine residues by sulfhydration, also known as …

Metagenomics of the gut microbiome in Parkinson's disease: prodromal changes

N Palacios, J Wilkinson, K Bjornevik… - Annals of …, 2023 - Wiley Online Library
Objective Prior studies on the gut microbiome in Parkinson's disease (PD) have yielded
conflicting results, and few studies have focused on prodromal (premotor) PD or used …

Formation of iron-rich encrustation layer on anammox granules for high load stress resistance: Performance, advantages, and mechanisms

Y Wang, S Nie, Q Yuan, Y Liu, Y Meng, F Luan - Bioresource Technology, 2024 - Elsevier
Anaerobic ammonia oxidation (anammox) is a cost-effective technology but its performance
can be seriously inhibited by high load stress. This study has created an innovative iron-rich …

Essential role of sulfide oxidation in brain health and neurological disorders

E Kanemaru, F Ichinose - Pharmacology & Therapeutics, 2024 - Elsevier
Hydrogen sulfide (H 2 S) is an environmental hazard well known for its neurotoxicity. In
mammalian cells, H 2 S is predominantly generated by transsulfuration pathway enzymes. In …

Gut microbiota and Parkinson's disease: potential links and the role of fecal microbiota transplantation

M Feng, Z Zou, P Shou, W Peng, M Liu… - Frontiers in Aging …, 2024 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disease
worldwide and seriously affects the quality of life of elderly patients. PD is characterized by …

Parkinson's Disease and the Microbiota-Gut-Brain Axis: Metabolites, Mechanisms, and Innovative Therapeutic Strategies Targeting the Gut Microbiota

Z Ran, BR Mu, DM Wang, QH Ma, MH Lu - Molecular Neurobiology, 2024 - Springer
The human gut microbiota is diverse and abundant and plays important roles in regulating
health by participating in metabolism and controlling physiological activities. The gut …

Parkinson's disease: a tale of many players

EKJ Pauwels, GJ Boer - Medical Principles and Practice, 2023 - karger.com
In 2020, more than 9 million patients suffering from ParkinsonLs disease (PD) were reported
worldwide, and studies predict that the burden of this disease will grow substantially in …

[HTML][HTML] The causal effects of gut microbiota on quantitative susceptibility mapping (QSM) and T2* imaging-derived phenotypes: insights from a Mendelian …

B Huang, L Yang, F Liu, S Gou… - Quantitative Imaging in …, 2024 - pmc.ncbi.nlm.nih.gov
Background Gut microbiota are associated with brain imaging-derived phenotypes (IDPs);
however, the specific causal relationship between the gut microbiota and brain iron-related …

An efficient pipeline for creating metagenomic-assembled genomes from ancient oral microbiomes

FJ Standeven, G Dahlquist-Axe, CF Speller… - bioRxiv, 2024 - biorxiv.org
Metagenomic-assembled genomes (MAGs) are difficult to recover from ancient DNA (aDNA)
due to substantial fragmentation, degradation, and multi-source contamination. These …