Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a novel epidemic
strain of Betacoronavirus that is responsible for the current viral pandemic, coronavirus …

Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2),
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …

The global spread of SARS-CoV-2 is posing major public health challenges. One feature of
SARS-CoV-2 spike protein is the insertion of multi-basic residues at the S1/S2 subunit …

Alzheimer's disease (AD) is characterized by the presence of amyloid β (Aβ) plaques, tau
tangles, inflammation, and loss of cognitive function. Genetic variation in a cholesterol …

Sterol regulatory element binding protein-2 (SREBP-2) is activated by cytokines or
pathogen, such as virus or bacteria, but its association with diminished cholesterol levels in …

Abstract Coronavirus disease 2019 (COVID-19), which is caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is a life-threatening disease, especially …

We aim to study the association of hyperlipidemia and statin use with COVID-19 severity. We
analysed a retrospective cohort of 717 patients admitted to a tertiary centre in Singapore for …

Membrane rafts are dynamic, small (10–200 nm) domains enriched with cholesterol and
sphingolipids that compartmentalize cellular processes. Rafts participate in roles essential to …

We investigate binding of linoleate and other potential ligands to the recently discovered
fatty acid binding site in the SARS‐CoV‐2 spike protein, using docking and molecular …

COVID-19 is also manifested with hypercoagulability, pulmonary intravascular coagulation,
microangiopathy, and venous thromboembolism (VTE) or arterial thrombosis. Predisposing …