[HTML][HTML] Nanotechnology based drug delivery systems for the treatment of anterior segment eye diseases

AL Onugwu, CS Nwagwu, OS Onugwu… - Journal of Controlled …, 2023 - Elsevier
Diseases affecting the anterior segment of the eye are the primary causes of vision
impairment and blindness globally. Drug administration through the topical ocular route is …

Nanotechnology-based ocular drug delivery systems: recent advances and future prospects

S Li, L Chen, Y Fu - Journal of Nanobiotechnology, 2023 - Springer
Ocular drug delivery has constantly challenged ophthalmologists and drug delivery
scientists due to various anatomical and physiological barriers. Static and dynamic ocular …

Lipid nanoparticles as a promising drug delivery carrier for topical ocular therapy—an overview on recent advances

S Jacob, AB Nair, J Shah, S Gupta, SHS Boddu… - Pharmaceutics, 2022 - mdpi.com
Due to complicated anatomical and physical properties, targeted drug delivery to ocular
tissues continues to be a key challenge for formulation scientists. Various attempts are …

Nanoemulsion applications in photodynamic therapy

S Moghassemi, A Dadashzadeh, RB Azevedo… - Journal of Controlled …, 2022 - Elsevier
Nanoemulsion, or nanoscaled-size emulsions, is a thermodynamically stable system formed
by blending two immiscible liquids, blended with an emulsifying agent to produce a single …

Therapeutic nanoemulsions in ophthalmic drug administration: Concept in formulations and characterization techniques for ocular drug delivery

M Singh, S Bharadwaj, KE Lee, SG Kang - Journal of Controlled Release, 2020 - Elsevier
The eye is the specialized part of the body and is comprised of numerous physiological
ocular barriers that limit the drug absorption at the action site. Regardless of various efforts …

Ophthalmic nanoemulsions: From composition to technological processes and quality control

A Gawin-Mikołajewicz, KP Nartowski… - Molecular …, 2021 - ACS Publications
Nanoemulsions are considered as the most promising solution to improve the delivery of
ophthalmic drugs. The design of ophthalmic nanoemulsions requires an extensive …

Nano-based drug delivery system: recent strategies for the treatment of ocular disease and future perspective

Z Qamar, FF Qizilbash, MK Iqubal, A Ali… - Recent Patents on …, 2019 - ingentaconnect.com
The structure of the eye is very complex in nature which makes it a challenging task for
pharmaceutical researchers to deliver the drug at the desired sites via different routes of …

Breaking barriers in eye treatment: Polymeric nano-based drug-delivery system for anterior segment diseases and glaucoma

KY Wu, S Ashkar, S Jain, M Marchand, SD Tran - Polymers, 2023 - mdpi.com
The eye has anatomical structures that function as robust static and dynamic barriers,
limiting the penetration, residence time, and bioavailability of medications administered …

Development of thermosensitive in situ gel nanoemulsions for ocular delivery of acyclovir

MM Mahboobian, M Mohammadi, Z Mansouri - Journal of Drug Delivery …, 2020 - Elsevier
The aim of the current study was to formulate thermosensitive in situ gel nanoemulsions
(NEs) containing acyclovir (ACV) for ocular drug delivery and evaluate their ex vivo corneal …

Lipid-based nanocarriers for ocular drug delivery: An updated review

B Das, AK Nayak, S Mallick - Journal of Drug Delivery Science and …, 2022 - Elsevier
Recent years have witnessed a boom in ocular nanomedicine research with a number of
lipid-based nanocarriers such as liposomes, niosomes, cubosomes, nanoemulsions, solid …