Calciphylaxis: risk factors, diagnosis, and treatment

SU Nigwekar, D Kroshinsky, RM Nazarian… - American Journal of …, 2015 - Elsevier
Calciphylaxis is a rare but devastating condition that has continued to challenge the medical
community since its early descriptions in the scientific literature many decades ago. It is …

Calcinosis cutis: part I. Diagnostic pathway

N Reiter, L El-Shabrawi, B Leinweber… - Journal of the American …, 2011 - Elsevier
Calcinosis cutis is characterized by the deposition of insoluble calcium salts in the skin and
subcutaneous tissue. The syndrome is separated into five subtypes: dystrophic calcification …

Sodium thiosulfate therapy for calcific uremic arteriolopathy

SU Nigwekar, SM Brunelli, D Meade… - Clinical journal of the …, 2013 - journals.lww.com
Results Mean age of the cohort was 55 years, and 74% of patients were women. Median
STS dose was 25 g, and median number of doses was 38. Among surveyed patients, CUA …

Fetuin-mineral complex reflects extraosseous calcification stress in CKD

T Hamano, I Matsui, S Mikami, K Tomida… - Journal of the …, 2010 - journals.lww.com
Fetuin-A is an important inhibitor of extraosseous calcification, but some of the studies that
used ELISAs did not identify a significant relationship between serum fetuin-A levels and …

[HTML][HTML] Treatment of calciphylaxis in CKD: a systematic review and meta-analysis

S Udomkarnjananun, K Kongnatthasate… - Kidney international …, 2019 - Elsevier
Background Calciphylaxis is a life-threatening complication of chronic kidney disease
(CKD). To inform clinical practice, we performed a systematic review of case reports, case …

Calcification is associated with loss of functional calcium-sensing receptor in vascular smooth muscle cells

M Alam, JP Kirton, FL Wilkinson, E Towers… - Cardiovascular …, 2009 - academic.oup.com
Aims Vascular calcification (VC) is highly correlated with increased morbidity and mortality in
advanced chronic kidney disease (CKD) patients. Allosteric modulation of the calcium …

Calciphylaxis: a systematic review of existing and emerging therapies

C Vedvyas, LS Winterfield, RA Vleugels - Journal of the American Academy …, 2012 - Elsevier
Calciphylaxis, also known as calcific uremic arteriolopathy, is a cutaneous ischemic small
vessel vasculopathy seen in 1 to 4% of patients with chronic kidney disease on …

Multi-intervention management of calciphylaxis: a report of 7 cases

C Baldwin, M Farah, M Leung, P Taylor, R Werb… - American Journal of …, 2011 - Elsevier
Calcific uremic arteriolopathy (calciphylaxis) is a devastating but rare complication seen
predominantly in dialysis patients that often is fatal. Because of the rarity of the disease and …

Cutaneous manifestations of ESRD

TA Galperin, AJ Cronin, KS Leslie - Clinical Journal of the …, 2014 - journals.lww.com
A broad range of skin diseases occurs in patients with ESRD: from the benign and
asymptomatic to the physically disabling and life-threatening. Many of them negatively …

[HTML][HTML] Calcium-sensing receptor, calcimimetics, and cardiovascular calcifications in chronic kidney disease

PAU Torres, M De Broe - Kidney international, 2012 - Elsevier
Renal function impairment goes along with a disturbed calcium, phosphate, and vitamin D
metabolism, resulting in secondary hyperparathyroidism (sHPT). These mineral metabolism …