Lipid droplets are storage organelles at the centre of lipid and energy homeostasis. They
have a unique architecture consisting of a hydrophobic core of neutral lipids, which is …

In cells, lipids are stored in lipid droplets, dynamic organelles that adapt their size,
abundance, lipid and protein composition and organelle interactions to metabolic changes …

Lipid composition determines organelle identity; however, whether the lipid composition of
the inner nuclear membrane (INM) domain of the ER contributes to its identity is not known …

Amphipathic helices (AHs), a secondary feature found in many proteins, are defined by their
structure and by the segregation of hydrophobic and polar residues between two faces of …

Lipodystrophies are the result of a range of inherited and acquired causes, but all are
characterized by perturbations in white adipose tissue function and, in many instances, its …

Lipodystrophies have been recognized since at least the nineteenth century and, despite
their rarity, tended to attract considerable medical attention because of the severity and …

The cell nucleus is best known as the container of the genome. Its envelope provides a
barrier for passive macromolecule diffusion, which enhances the control of gene expression …

The origin and physiological significance of lipid droplets (LDs) in the nucleus is not clear.
Here we show that nuclear LDs in hepatocytes are derived from apolipoprotein B (ApoB) …

As eukaryotic cells progress through cell division, the nuclear envelope (NE) membrane
must expand to accommodate the formation of progeny nuclei. In Saccharomyces …

Lipids play crucial roles in many biological processes. Mapping spatial distributions and
examining the metabolic dynamics of different lipid subtypes in cells and tissues are critical …