Since the discovery of ocular dominance plasticity, neuroscientists have understood that
changes in visual experience during a discrete developmental time, the critical period …

During cortical development and throughout adulthood, oligodendrocytes add myelin
internodes to glutamatergic projection neurons and GABAergic inhibitory neurons. In …

To test the hypothesized crucial role of microglia in the developmental refinement of neural
circuitry, we depleted microglia from mice of both sexes with PLX5622 and examined the …

Genetic risk factors for neurodegenerative disorders, such as Alzheimer's disease (AD), are
expressed throughout the life span. How these risk factors affect early brain development …

Subanesthetic ketamine evokes rapid and long-lasting antidepressant effects in human
patients. The mechanism for ketamine's effects remains elusive, but ketamine may broadly …

Microglia populate the early developing brain and mediate pruning of the central synapses.
Yet, little is known on their functional significance in shaping the developing cortical circuits …

C1q, the initiator of the classical complement cascade, mediates synapse elimination in the
postnatal mouse dorsolateral geniculate nucleus of the thalamus and sensorimotor cortex …

Purpose To compare the effectiveness and efficiency of supervised dichoptic action‐
videogame play to occlusion therapy in children with amblyopia. Methods Newly diagnosed …

Study of the neural deficits caused by mismatched binocular vision in early childhood has
predominantly focused on circuits in the primary visual cortex (V1). Recent evidence has …

Visual plasticity is classically considered to occur essentially in the primary and secondary
cortical areas. Subcortical visual areas such as the dorsal lateral geniculate nucleus (dLGN) …