The intraepithelial lymphocytes (IELs) that reside within the epithelium of the intestine form
one of the main branches of the immune system. As IELs are located at this critical interface …

The lymphoid tissues associated with the intestine are exposed continuously to antigen and
are the largest part of the immune system. Many lymphocytes are found in organised tissues …

The mouse thymus contains a mature T cell subset that is distinguishable from the
mainstream thymocytes by several characteristics. It is restricted in its usage of T cell …

Conventional major histocompatibility complex (MHC) class I genes encode molecules that
present intracellular peptide antigens to T cells. They are ubiquitously expressed and …

Major histocompatibility complex (MHC) class I genes typically encode polymorphic peptide-
binding chains which are ubiquitously expressed and mediate the recognition of intracellular …

Rare major histocompatibility complex (MHC) class I-like CD1-specific T cells have been
isolated from human blood, but it has not been determined whether these clones are part of …

BACKGROUND AND AIM Intestinal epithelial cells (IEC) are thought to participate in the
mucosal defence against bacteria and in the regulation of mucosal tissue homeostasis …

Food allergies affect as many as 6% of young children, most of whom “outgrow” the
sensitivity, and about 2% of the general population. Although any food may provoke a …

Murine CD1 has been implicated in the development and function of an unusual subset of T
cells, termed natural T (NT) cells, that coexpress the T cell receptor (TCR) and the natural …

The MHC fold is found in proteins that have a range of functions in the maintenance of an
organism's health, from immune regulation to fat metabolism. Well adapted for antigen …