The pleiotropic cytokine interleukin-6 (IL-6) is emerging as a molecule with both beneficial
and destructive potentials. It can exert opposing actions triggering either neuron survival …

The most commonly recognized behavioral patterns of animals and people at the onset of
febrile infectious diseases are lethargy, depression, anorexia, and reduction in grooming …

INTRODUCTION Antibody function is often considered static and mostly determined by
isotype and subclass. The conserved N-linked glycan at position 297 in the Fc domain of …

Publisher Summary This chapter focuses on structure and expression of interleukin-6 (IL-6),
which is a cytokine with pleiotropic activities that plays a central role in host defense. IL-6 …

Interleukin-1β (IL-1β), interleukin-2 (IL-2), and interleukin-6 (IL-6) were measured in the
cerebrospinal fluid (CSF) and plasma of 12 control subjects, 11 sporadic Alzheimer's …

Abstract Interleukin-6 (IL-6) shares several biologic properties with IL-1, including
hematopoietin-1 activity and stimulation of T cells. Because many of their biologic activities …

Castleman's disease is a syndrome consisting of giant lymph node hyperplasia with plasma
cell infiltration, fever, anemia, hypergammaglobulinemia, and an increase in the plasma …

Forty critically ill surgical patients with documented infections were studied during their stay
in an intensive care unit. Among these patients, 19 developed septic shock and 16 died, 9 of …

Control of receptor function The availability of cytokines and growth factors is controlled by
their expression. There are multiple ways to regulate receptor function:(i) expression of …

It has been over 30 years since Atkins (8) wrote a comprehensive review on the
pathogenesis of fever for Physiologica~ Z Reviews. In the intervening years our …