Genetic and epigenetic basis of hepatoblastoma diversity

G Nagae, S Yamamoto, M Fujita, T Fujita… - Nature …, 2021 - nature.com
Hepatoblastoma (HB) is the most common pediatric liver malignancy; however, hereditary
predisposition and acquired molecular aberrations related to HB clinicopathological …

Virtual reality in chemotherapy support for the treatment of physical functions, fear, and quality of life in pediatric cancer patients: A systematic review and meta …

O Czech, S Rutkowski, A Kowaluk, P Kiper… - Frontiers in Public …, 2023 - frontiersin.org
Background Appropriately selected complementary therapies, such as virtual reality (VR)
and active video games (AVG), provide support to young patients during the process of …

Genome-wide mapping of cancer dependency genes and genetic modifiers of chemotherapy in high-risk hepatoblastoma

J Fang, S Singh, C Cheng, S Natarajan… - Nature …, 2023 - nature.com
A lack of relevant genetic models and cell lines hampers our understanding of
hepatoblastoma pathogenesis and the development of new therapies for this neoplasm …

Maternal body mass index, diabetes, and gestational weight gain and risk for pediatric cancer in offspring: a systematic review and meta-analysis

AR Marley, A Domingues, T Ghosh… - JNCI cancer …, 2022 - academic.oup.com
Background Pediatric cancer incidence has steadily increased concurrent with rising adult
obesity, but associations between maternal obesity and associated comorbidities and …

Incidence and 5‐year survival of children and adolescents with hepatoblastoma in the United States

JA Kahla, DA Siegel, S Dai, PJ Lupo… - Pediatric blood & …, 2022 - Wiley Online Library
Objective Hepatoblastoma (HB) is the most common pediatric primary malignant liver tumor,
its incidence has been increasing worldwide, but recent changes in incidence and outcomes …

[HTML][HTML] International society of paediatric surgical oncology (IPSO) surgical practice guidelines

SCV Abib, CH Chui, S Cox, AH Abdelhafeez… - …, 2022 - ncbi.nlm.nih.gov
Most children with tumors will require one or more surgical interventions as part of the care
and treatment, including making a diagnosis, obtaining adequate venous access …

Outcome and late complications of hepatoblastomas treated using the Japanese Study Group for Pediatric Liver Tumor 2 Protocol

E Hiyama, T Hishiki, K Watanabe, K Ida… - Journal of Clinical …, 2020 - ascopubs.org
PURPOSE We report here the outcomes and late effects of the Japanese Study Group for
Pediatric Liver Tumors (JPLT)-2 protocol, on the basis of cisplatin-tetrahydropyranyl …

MDM4 inhibition: a novel therapeutic strategy to reactivate p53 in hepatoblastoma

SE Woodfield, Y Shi, RH Patel, Z Chen, AP Shah… - Scientific reports, 2021 - nature.com
Hepatoblastoma (HB) is the most common pediatric liver malignancy. High-risk patients
have poor survival, and current chemotherapies are associated with significant toxicities …

[HTML][HTML] Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults

P Sumazin, TL Peters, SF Sarabia, HR Kim… - Journal of …, 2022 - Elsevier
Background & Aims Hepatoblastoma (HB) and hepatocellular carcinoma (HCC) are the
predominant liver cancers in children, though their respective treatment options and …

Hepatoblastoma

J Hager, CM Sergi - Exon Publications, 2021 - exonpublications.com
Hepatoblastoma is the most common liver cancer in children aged 3 years and younger. The
differential diagnosis of this neoplasm is crucial for the proper management. Recent …