Chemical strategies to engineer hydrogels for cell culture

J Lou, DJ Mooney - Nature Reviews Chemistry, 2022 - nature.com
Two-dimensional and three-dimensional cell culture systems are widely used for biological
studies, and are the basis of the organoid, tissue engineering and organ-on-chip research …

[HTML][HTML] 3D printing of hydrogels: Rational design strategies and emerging biomedical applications

J Li, C Wu, PK Chu, M Gelinsky - Materials Science and Engineering: R …, 2020 - Elsevier
Abstract 3D printing alias additive manufacturing can transform 3D virtual models created by
computer-aided design (CAD) into physical 3D objects in a layer-by-layer manner …

Polyphenol scaffolds in tissue engineering

X Zhang, Z Li, P Yang, G Duan, X Liu, Z Gu, Y Li - Materials Horizons, 2021 - pubs.rsc.org
Polyphenols are a class of ubiquitous compounds distributed in nature, with fascinating
inherent biocompatible, bioadhesive, antioxidant, and antibacterial properties. The unique …

Advancing models of neural development with biomaterials

JG Roth, MS Huang, TL Li, VR Feig, Y Jiang… - Nature Reviews …, 2021 - nature.com
Human pluripotent stem cells have emerged as a promising in vitro model system for
studying the brain. Two-dimensional and three-dimensional cell culture paradigms have …

Chitin and chitosan-based support materials for enzyme immobilization and biotechnological applications

ML Verma, S Kumar, A Das, JS Randhawa… - Environmental …, 2020 - Springer
Enzymes of industrial importance are primarily employed for biotechnological applications.
However, high-cost and instability issues of purified enzymes hamper their usage. Multiple …

Designing degradable hydrogels for orthogonal control of cell microenvironments

PM Kharkar, KL Kiick, AM Kloxin - Chemical Society Reviews, 2013 - pubs.rsc.org
Degradable and cell-compatible hydrogels can be designed to mimic the physical and
biochemical characteristics of native extracellular matrices and provide tunability of …

Achieving controlled biomolecule–biomaterial conjugation

CD Spicer, ET Pashuck, MM Stevens - Chemical reviews, 2018 - ACS Publications
The conjugation of biomolecules can impart materials with the bioactivity necessary to
modulate specific cell behaviors. While the biological roles of particular polypeptide …

2D versus 3D human induced pluripotent stem cell-derived cultures for neurodegenerative disease modelling

EGZ Centeno, H Cimarosti, A Bithell - Molecular neurodegeneration, 2018 - Springer
Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD),
Huntington's disease (HD) and amyotrophic lateral sclerosis (ALS), affect millions of people …

pH-controlled nucleolin targeted release of dual drug from chitosan-gold based aptamer functionalized nano drug delivery system for improved glioblastoma treatment

A Sathiyaseelan, K Saravanakumar… - Carbohydrate …, 2021 - Elsevier
This study developed the pH, and over-expressed nucleolin receptor responsive nano-drug
delivery system (nDDS) composed by bio-synthesized gold nanoparticles (Au NPs) …

Hydrogels for tissue engineering and regenerative medicine

JA Hunt, R Chen, T van Veen, N Bryan - Journal of Materials Chemistry …, 2014 - pubs.rsc.org
Injectable hydrogels have become an incredibly prolific area of research in the field of tissue
engineering and regenerative medicine, because of their high water content, mechanical …