Lithium has been used for the treatment of bipolar disorder (BD) for the last sixty or more
years, and recent studies with more reliable designs and updated guidelines have …

Lithium is the most effective and well established treatment for bipolar disorder, and it has a
broad array of effects within cellular pathways. However, the specific processes through …

Over the last six decades, lithium has been considered the gold standard treatment for the
long-term management of bipolar disorder due to its efficacy in preventing both manic and …

Lithium has been used in the treatment of bipolar disorders for decades, but the exact
mechanisms of action remain elusive to this day. Recent evidence suggests that lithium is …

Multiple genetic, metabolic, and environmental abnormalities are known to contribute to the
pathogenesis of Alzheimer's dementia (AD). If all of those abnormalities were addressed it …

Lithium remains an effective option in the treatment of bipolar disorder (BD). Thus, we aim to
characterize the pharmaco-epidemiological patterns of lithium use internationally over time …

Objectives The putative neuroprotective effects of lithium treatment rely on the fact that it
modulates several homeostatic mechanisms involved in the neurotrophic response …

Used as a supplement to psychotherapy, pharmacotherapy that addresses all of the known
metabolic and genetic contributions to the pathogenesis of psychiatric conditions caused by …

Background Rapid-eye movement (REM) sleep deprivation (SD) can induce manic-like
behaviors in rodents. On the other hand, lithium, as one of the oldest drugs used in …

The pathological process of Parkinson's disease (PD) is closely associated with the death of
nigral neurons, for which an effective treatment has yet to be found. Lithium, one of the most …