[HTML][HTML] Mitochondrial alterations in fatty liver diseases

B Fromenty, M Roden - Journal of hepatology, 2023 - Elsevier
Fatty liver diseases can result from common metabolic diseases, as well as from xenobiotic
exposure and excessive alcohol use, all of which have been shown to exert toxic effects on …

Role of mitochondrial dynamics and mitophagy of vascular smooth muscle cell proliferation and migration in progression of atherosclerosis

DTN Huynh, KS Heo - Archives of Pharmacal Research, 2021 - Springer
Vascular smooth muscle cell (VSMC) proliferation and migration are critical events that
contribute to the pathogenesis of vascular diseases such as atherosclerosis, restenosis, and …

[HTML][HTML] The role of LSM1 in breast cancer: shaping metabolism and tumor-associated macrophage infiltration

YDT Tzeng, JH Hsiao, PY Chu, LM Tseng… - Pharmacological …, 2023 - Elsevier
LSM1 is part of the cytoplasmic protein complex Lsm1–7-Pat1 and is likely involved in pre-
mRNA degradation by aiding U4/U6 snRNP formation. More research is needed to uncover …

[HTML][HTML] Mitoquinone shifts energy metabolism to reduce ROS-induced oxeiptosis in female granulosa cells and mouse oocytes

KH Tsui, CJ Li - Aging (Albany NY), 2023 - ncbi.nlm.nih.gov
The female reproductive system is quite sensitive to regulation, and external environmental
stimuli may cause oxidative stress which in turn may lead to accelerated aging and …

The role of mitochondria in the pathophysiology and treatment of common metabolic diseases in humans

A Georgiev, C Granata… - American Journal of …, 2022 - journals.physiology.org
Common metabolic diseases such as obesity, type 2 diabetes mellitus, and nonalcoholic
fatty liver disease significantly contribute to morbidity and mortality worldwide. They are …

In Vitro and In Vivo Antitumor Assay of Mitochondrially Targeted Fluorescent Half-Sandwich Iridium (III) Pyridine Complexes

L Wang, X Liu, Y Wu, X He, X Guo, W Gao… - Inorganic …, 2023 - ACS Publications
Half-sandwich iridium (III) complexes show potential value in the anticancer field. However,
complexes with favorable luminescence performance are rare, which limits further …

Enteropathogenic Escherichia coli regulates host-cell mitochondrial morphology

JL Roxas, S Ramamurthy, K Cocchi, I Rutins… - Gut …, 2022 - Taylor & Francis
The diarrheagenic pathogen enteropathogenic Escherichia coli is responsible for significant
childhood mortality and morbidity. EPEC and related attaching-and-effacing (A/E) pathogens …

[HTML][HTML] Boosting mitochondrial function and metabolism in aging female germ cells with dual ROCK/ROS inhibition

WP Su, CJ Li, LT Lin, PH Lin, ZH Wen, JJC Sheu… - Biomedicine & …, 2023 - Elsevier
The decline in oocyte quality with age is an irreversible process that results in low fertility.
Reproductive aging causes an increase in oocyte aneuploidy leading to a decrease in …

Epithelial OPA1 links mitochondrial fusion to inflammatory bowel disease

LL Bao, YQ Yu, M González-Acera… - Science Translational …, 2025 - science.org
Dysregulation at the intestinal epithelial barrier is a driver of inflammatory bowel disease
(IBD). However, the molecular mechanisms of barrier failure are not well understood. Here …

Mitochondrial dynamics in pulmonary disease: Implications for the potential therapeutics

H Li, X Dai, J Zhou, Y Wang, S Zhang… - Journal of Cellular …, 2024 - Wiley Online Library
Mitochondria are dynamic organelles that continuously undergo fusion/fission to maintain
normal cell physiological activities and energy metabolism. When mitochondrial dynamics is …