Research in the field of bioinorganic chemistry has been stimulated by the worldwide
success of the anticancer drug cisplatin. 40 years after the first report about its biological …

The five-membered aromatic heterocycles containing oxygen and sulfur are key building
blocks used in medicinal chemistry applications. Furans, thiophenes and related azole …

Using a combination of tandem affinity purification tagging and mass spectrometry, we
characterized a novel, evolutionarily conserved protein phosphatase 4 (PP4)-containing …

Herbal medicine is one of the forms of traditional medical practice. Traditional Chinese
medicine (TCM) and traditional Vietnamese medicine (TVM) are well-known for their long …

Metal complexes afford an opportunity for the discovery of new antitumour drugs with truly
novel mechanisms of action. Various tactics and some new concepts have been employed …

Natural product extracts are a rich source of small molecules that display antitumor activity.
Cantharidin, in the form of the dried body of the Chinese blister beetles: Mylabris phalerata …

An unsolved question is how platinum derivatives used for solid cancer therapy cause
peripheral neuropathy in patients and apoptosis in “in vitro” models of chemotherapy …

This review summarizes the progress that has been made recently in the medicinal
chemistry of cantharidin, a potent antitumor agent from traditional Chinese medicine …

Abstract Solubility of cis-5-norbornene-endo-2, 3-dicarboxylic anhydride (carbic anhydride)
in fourteen pure solvents including methyl acetate (MAC), ethyl acetate (EAC), n-propyl …

The resistance to oxaliplatin (L-OHP) is a major obstacle to ideal therapeutic outcomes in
colorectal cancer. Photodynamic therapy (PDT) induces tumor damage through …