Biscoumarin–pyrimidine conjugates as potent anticancer agents and binding mechanism of hit candidate with human serum albumin
In our continuing efforts to develop therapeutically active coumarin‐based compounds, a
series of new C4–C4′ biscoumarin–pyrimidine conjugates (1a–l) was synthesized via SN2 …
series of new C4–C4′ biscoumarin–pyrimidine conjugates (1a–l) was synthesized via SN2 …
Potent drug candidature of an ONS donor tethered copper (II) complex: Anticancer activity, cytotoxicity and spectroscopically approached BSA binding studies
In our continued efforts to develop metal based therapeutic agents, we have synthesized a
novel copper (II) complex,[{Cu (hpdbal-sbdt)} 2](2) tethered with a biocompatible ONS 2 …
novel copper (II) complex,[{Cu (hpdbal-sbdt)} 2](2) tethered with a biocompatible ONS 2 …
Coumarin tethered cyclic imides as efficacious glucose uptake agents and investigation of hit candidate to probe its binding mechanism with human serum albumin
A series of novel coumarin-cyclic imide conjugates (1a–1j) were designed and synthesized
to evaluate their glucose uptake activity by insulin resistant liver hepatocyte carcinoma …
to evaluate their glucose uptake activity by insulin resistant liver hepatocyte carcinoma …
ON donor tethered copper (II) and vanadium (V) complexes as efficacious anti-TB and anti-fungal agents with spectroscopic approached HSA interactions
Antimicrobial drug resistance poses a significant threat worldwide, hence triggering an
urgent situation for developing feasible drugs. 3D-transition metal coordination complexes …
urgent situation for developing feasible drugs. 3D-transition metal coordination complexes …
In vitro apoptosis-induction, antiproliferative and BSA binding studies of a oxidovanadium (V) complex
In our ongoing efforts to develop novel trace metal complexes with therapeutically
interesting properties, a neutral mono nuclear oxidomethoxidovanadium (V) complex,[VVO …
interesting properties, a neutral mono nuclear oxidomethoxidovanadium (V) complex,[VVO …
ONS donor entwined iron (III) and cobalt (III) complexes with exemplary safety profile as potent anticancer and glucose uptake agents
The global increasing burden of non-communicable diseases such as cancer and diabetes
has generated an immediate need for the development of sustainable drugs. Transition …
has generated an immediate need for the development of sustainable drugs. Transition …
Oxidovanadium (IV) and iron (III) complexes with O2N2 donor linkage as plausible antidiabetic candidates: Synthesis, structural characterizations, glucose uptake …
With the upsurging cases of type II diabetic patients, the demand for safe and effective oral
antidiabetic drugs is also increasing. Coordination complexes have proven their mettle as …
antidiabetic drugs is also increasing. Coordination complexes have proven their mettle as …
A manganese (II) complex tethered with S-benzyldithiocarbazate Schiff base: Synthesis, characterization, in-vitro therapeutic activity and protein interaction studies
There is an urgent need to eliminate the era of superbugs through design and development
of novel and sustainable drugs. Transition metal complexes can be one of the hopes for …
of novel and sustainable drugs. Transition metal complexes can be one of the hopes for …
[PDF][PDF] Chromium (III) complexes of metformin, dapagliflozin, vildagliptin and glimepiride potentiate antidiabetic activity in animal model
Introduction: Diabetes is a chronic disease which increases morbidity, mortality along with
social and economic costs. Chromium [Cr (III)] is a trace element which plays an important …
social and economic costs. Chromium [Cr (III)] is a trace element which plays an important …
Synthesis, characterization, antimicrobial and antitubercular evaluation of nickel (II) complexes of ON donor quinoline-hydrazide core
In the current work, non-toxic and safe Ni (II) complexes of unsymmetrical Schiff base ligand
derived from Quinoline hybrid and isoniazid, viz.[NiII (Quibal-INH) 2](1),[NiII (Quibal …
derived from Quinoline hybrid and isoniazid, viz.[NiII (Quibal-INH) 2](1),[NiII (Quibal …