Stem cells as a potential therapy for diabetes mellitus: a call-to-action in Latin America

MA Solis, I Moreno Velásquez, R Correa… - Diabetology & metabolic …, 2019 - Springer
Latin America is a fast-growing region that currently faces unique challenges in the
treatment of all forms of diabetes mellitus. The burden of this disease will be even greater in …

Role of poly (ADP-ribose) polymerase-1 in regulating human islet cell differentiation

N Dadheech, A Srivastava, RG Shah, GM Shah… - Scientific Reports, 2022 - nature.com
Abstract Poly (ADP-ribose) polymerase-1 (PARP1), a fundamental DNA repair enzyme, is
known to regulate β cell death, replication, and insulin secretion. PARP1 knockout (KO) mice …

Stem cells: a renewable source of pancreatic β-cells and future for diabetes treatment

S Kh, KH Haider - Stem cells: latest advances, 2021 - Springer
According to the figures released by the International Diabetes Federation (IDF), there were
more than 4.8 million diabetes-related deaths in 2012 alone, and a total of 371 million …

Influence of metabolically compromised Adipose derived stem cell secretome on islet differentiation and functionality

G Bhardwaj, M Vakani, A Srivastava, K Rawal… - Experimental Cell …, 2022 - Elsevier
Islet integrity plays a major role in maintaining glucose homeostasis and thus replenishment
of damaged islets by differentiation of resident endocrine progenitors into neo islets …

Stammzellen: Eine erneuerbare Quelle für β-Zellen der Bauchspeicheldrüse und die Zukunft der Diabetesbehandlung

S Kh, KH Haider - Stammzellen: Neueste Fortschritte, 2023 - Springer
Zusammenfassung Nach Angaben der International Diabetes Federation (IDF) gab es allein
im Jahr 2012 mehr als 4, 8 Mio. diabetesbedingte Todesfälle, und insgesamt wurde bei 371 …

Catalytic-independent function of PARP-1 is essential in regulating human islet-cell differentiation from stem cells

N Dadheech, A Srivastava, RG Shah, GM Shah… - 2022 - researchsquare.com
Abstract Poly (ADP) Ribose Polymerase-1 (PARP-1), a fundamental DNA repair enzyme is
known to regulate β cell death, replication, and insulin secretion. PARP-1 knockout (KO) …