Microbial regulation of host physiology by short-chain fatty acids

B van der Hee, JM Wells - Trends in Microbiology, 2021 - cell.com
Our ancestral diet consisted of much more nondigestible fiber than that of many societies
today. Thus, from an evolutionary perspective the human genome and its physiological and …

SCFA: mechanisms and functional importance in the gut

C Martin-Gallausiaux, L Marinelli… - Proceedings of the …, 2021 - cambridge.org
In recent years, the importance of the gut microbiota in human health has been revealed and
many publications have highlighted its role as a key component of human physiology …

The role of short-chain fatty acids in microbiota–gut–brain communication

B Dalile, L Van Oudenhove, B Vervliet… - Nature reviews …, 2019 - nature.com
Short-chain fatty acids (SCFAs), the main metabolites produced by bacterial fermentation of
dietary fibre in the gastrointestinal tract, are speculated to have a key role in microbiota–gut …

Structural basis of odorant recognition by a human odorant receptor

CB Billesbølle, CA de March, WJC van der Velden… - Nature, 2023 - nature.com
Our sense of smell enables us to navigate a vast space of chemically diverse odour
molecules. This task is accomplished by the combinatorial activation of approximately 400 …

Therapeutic potential of ectopic olfactory and taste receptors

SJ Lee, I Depoortere, H Hatt - Nature Reviews Drug Discovery, 2019 - nature.com
Olfactory and taste receptors are expressed primarily in the nasal olfactory epithelium and
gustatory taste bud cells, where they transmit real-time sensory signals to the brain …

Microbial short-chain fatty acids and blood pressure regulation

JL Pluznick - Current hypertension reports, 2017 - Springer
Abstract Purpose of Review Microbial short-chain fatty acids (SCFAs) are byproducts of
microbial metabolism which can be absorbed into the bloodstream of the host, where they …

[HTML][HTML] Mechanisms of short-chain fatty acids derived from gut microbiota in Alzheimer's disease

X Qian, R Xie, X Liu, H Tang - Aging and disease, 2022 - ncbi.nlm.nih.gov
Short-chain fatty acids (SCFAs) are important metabolites derived from the gut microbiota
through fermentation of dietary fiber. SCFAs participate a number of physiological and …

[HTML][HTML] Role of short chain fatty acid receptors in intestinal physiology and pathophysiology

M Priyadarshini, KU Kotlo, PK Dudeja… - Comprehensive …, 2018 - ncbi.nlm.nih.gov
Nutrient sensing is a mechanism for organisms to sense their environment. In larger
animals, including humans, the intestinal tract is a major site of nutrient sensing for the body …

[HTML][HTML] Human olfactory receptors: novel cellular functions outside of the nose

D Maßberg, H Hatt - Physiological reviews, 2018 - journals.physiology.org
Olfactory receptors (ORs) are not exclusively expressed in the olfactory sensory neurons;
they are also observed outside of the olfactory system in all other human tissues tested to …

The effects of essential oils and terpenes in relation to their routes of intake and application

S Koyama, T Heinbockel - International journal of molecular sciences, 2020 - mdpi.com
Essential oils have been used in multiple ways, ie, inhaling, topically applying on the skin,
and drinking. Thus, there are three major routes of intake or application involved: the …