First discovered in the 1980's, granulysin has until recently been thought of solely as an
effector molecule present within cytotoxic immune cell populations, and involved in the direct …

Congenital toxoplasmosis is caused by the vertical transmission of infection from mother to
foetus through the placenta when a pregnant woman is infected with Toxoplasma gondii (T …

The combination of the activating killer cell Ig-like receptor 2DS1 (KIR2DS1) expressed by
maternal decidual natural killer cells (dNK) and the presence of its ligand, the HLA-C …

The placenta is a heterogeneous organ whose development involves complex interactions
of trophoblasts with decidual, vascular, and immune cells at the fetal–maternal interface. It …

Objective Autoimmune thyroid disease (AITD) is known to be associated with unexplained
infertility in women. Although the presence of antithyroid antibodies have been speculated to …

Toxoplasma gondii is an obligate intracellular parasite of phylum Apicomplexa that poses a
huge threat to pregnant hosts, and induces tragic outcomes for pregnant hosts, fetuses and …

The p53 protein is known for performing essential functions in the maintenance of genomic
stability in somatic cells and prevention of tumor formation. Studies of the p53 signaling …

Classical risk factors for endothelial dysfunction (ED), such as age, gender, total cholesterol,
high-density lipoprotein cholesterol, systolic blood pressure, and smoking history are utilised …

Simple Summary CD8+ T cells are prominent decidual cells in the third trimester of healthy
human pregnancy. They have a cytotoxic capacity which may control invasion of extravillous …

Apoptosis is essential for embryogenesis, organ metamorphosis, and tissue homeostasis. In
embryonic stem cells, self‐renewal is balanced with proliferative potential, inhibition of …