Glutathione (GSH) is the most abundant non-protein thiol present at millimolar
concentrations in mammalian tissues. As an important intracellular antioxidant, it acts as a …

Parkinson's Disease (PD) is a common and progressive neurodegenerative disorder
characterised by motor impairments as well as non-motor symptoms. While dopamine …

Glutathione is an essential metabolite for plant life best known for its role in the control of
reactive oxygen species (ROS). Glutathione is also involved in the detoxification of …

Mitochondria in aerobic eukaryotic cells are both the site of energy production and the
formation of harmful species, such as radicals and other reactive oxygen species, known as …

Cadmium (Cd), a category I human carcinogen, is a well-known widespread environmental
pollutant. Chronic Cd exposure affects different organs and tissues, such as the central …

Parkinson's Disease (PD) is characterized by the progressive loss of dopaminergic neurons
in the substantia nigra (SN), leading to motor and non-motor symptoms. While the exact …

Mitochondria are the main source of reactive oxygen species (ROS), most of them deriving
from the mitochondrial respiratory chain. Among the numerous enzymatic and non …

Abstract Manganese dioxide (MnO 2) nanoenzymes/nanozymes (MnO 2-NEs) are 1–100
nm nanomaterials that mimic catalytic, oxidative, peroxidase, and superoxide dismutase …

Glutathione (GSH) is the most abundant thiol in mammalian cells and plays a crucial role in
maintaining redox cellular homeostasis. The thiols of two GSH molecules can be oxidized to …

Cancer cells are characterized as highly proliferative at the expense of enhancement of
metabolic rate. Consequently, cancer cells rely on antioxidant defenses to overcome the …