Method to diversify cyanine chromophore functionality enables improved biomolecule tracking and intracellular imaging

SM Usama, SC Marker, DH Li… - Journal of the …, 2023 - ACS Publications
Heptamethine indocyanines are invaluable probes for near-infrared (NIR) imaging. Despite
broad use, there are only a few synthetic methods to assemble these molecules, and each …

Role of Polymethinic Chain Substitution on the Two‐Photon Absorption Cross‐section of Heptamethine Cyanine Dyes

CA Guarin, LG Mendoza‐Luna… - …, 2023 - Wiley Online Library
The effect on the two‐photon absorption of heptamethine cyanines (HMCy) upon
polymethinic chain substitution is explained via measurements with a femtosecond laser …

Novel dual-color fluorescence probe for monitoring the fluctuation of lysosomal polarity and viscosity during apoptosis

J Han, H Ren, X Luo, J Li, J Zhang - Microchemical Journal, 2024 - Elsevier
Apoptosis is pivotal in the pathogenesis of cancer and various other diseases. Real-time
monitoring of apoptosis is crucial for assessing cell viability and facilitating drug screening …

Fluorescent cyclopropyl ester probes are efficiently cleaved by endogenous carboxylesterase in mouse blood: implications for preclinical fluorescence imaging

HS Sanders, KM Atkinson, BD Smith - Supramolecular Chemistry, 2023 - Taylor & Francis
Prior studies have shown that fluorescent molecular probes based on cyclopropyl esters are
good substrates for butyrylcholine esterase (BChE), which is a biomarker of several human …