Background Drug overdose deaths have been rising since the early 1990s and is the
leading cause of injury death in the United States. Overdose from prescription opioids …

Background As physicians have increased opioid prescribing, overdose deaths from
pharmaceutical opioids have substantially increased in the United States. Naloxone …

These Guidelinesreview the use of medicines such as methadone, buprenorphine,
naltrexone and clonidine in combination with psychosocial support in the treatment of …

The historical patterns of opiate use show that sources and methods of access greatly
influence who is at risk. Today, there is evidence that an enormous increase in the …

Administering naloxone hydrochloride (naloxone) during an opioid overdose reverses the
overdose and can prevent death. Although typically delivered via intramuscular or …

BACKGROUND: Fatal opioid overdose is a significant cause of mortality among injection
drug users (IDUs). METHODS: We evaluated an overdose prevention and response training …

This paper examines overdose prevention programs based on peer administration of the
opioid antagonist naloxone. The data for this study consist of 40 interviews and participant …

The United States is in the midst of a prolonged and growing epidemic of accidental and
preventable deaths associated with overdoses of licit and illicit opioids. For more than 3 …

Aim To examine the impact of training in overdose management and naloxone provision on
the knowledge and confidence of current opiate users; and to record subsequent …

BACKGROUND: Drug users who are leaving/completing inpatient medication-free treatment
may, like drug users released from prison, have an elevated risk of dying from fatal …